Sarat Chandra G.

Technology Leader, Consultant | R&D Informatics Software Product Lead | Engineering Manager | ex-Genentech

Dublin, California, United States

About

* Founded Genentech's Chemoinformatics application and data platform, leveraging 20+ years of hands-on development and technology leadership experience. * Built and scaled enterprise platforms for small-molecule drug discovery across global R&D, supporting ADME, Biochemical Pharmacology, and Safety/Tox workflows. * Led cross-functional programs for 10+ years, aligning engineering strategy with scientific and executive priorities to deliver high-impact production-grade systems. * Modernized R&D infrastructure by championing cloud-native architectures, enterprise API suites, MLOps, and Agentic AI-assisted drug discovery. * Mentored high-performing engineering teams and influenced long-term informatics strategy through governance and steering committees at director and principal levels. * Earned the Genentech Research Recognition Award for Process Innovation three times for delivering measurable R&D impact. * Integrated and customized vendor data platforms including Dotmatics Vortex, Genedata Screener, Titian Mosaic, Seurat, Schrodinger Live Design, IDBS, BIOVIA, MD Oniro etc.

Experience

  • Technology Lead and Founding Member | Lead Technical Consultant at GoLivAILife Tech LLC
    Nov 2025 - Present · 9 mos

    * Founded a tech venture, defining the technical vision and architecture. Leading technical design, architecture of a core reusable AI platform suited for the life sciences industry. * Offering Technical Consulting/ Advisory/ Freelancing / Contract services in the areas of: Hands-on Full-Stack Engineering & Rapid Prototyping; AI-Native Development & Agentic Frameworks; Cloud-Native "Owner-Operator" Deployment

  • Genentech (24 yrs 3 mos)
    • Senior Principal Software Engineer | Technology Initiative Lead | Sr. Director-Level Principal
      Mar 2024 - Sep 2025 · 1 yr 7 mos

      * Led the COMPASS initiative on AWS EKS (Java, Kafka, MongoDB) to deliver a large-scale assay lifecycle solution, automating molecule progression. * Centralized localized APIs into a resilient Kubernetes infrastructure on AWS, improving R&D data access across enterprise products. * Architected a GenAI pilot using Amazon Bedrock and RAG-based LLMs to deploy text-to-SQL capabilities for drug discovery. * Mentored teams in hackathons to develop LLM agent PoCs, automating workflows and boosting SWE productivity with tools like Sourcegraph Cody.

    • Principal Software Engineer | Software Engineering Manager | Director-Level Principal
      Jan 2021 - Mar 2024 · 3 yrs 3 mos

      * Strategically led Data, Services, and API teams as Software Engineering Manager, modernizing infrastructure and engineering practices to drive "R&D Excellence." * Architected enterprise-scale data access and API initiatives that enabled critical AI/ML use cases. * Technical Lead for a React.js Dose Response Curve visualization tool, improving data analysis for Biochemical and Pharmacology teams. * Developed a reusable Python/React/Oracle API backend and libraries, creating a scalable foundation for Safety and Toxicology research.

    • Senior Software Engineer | Senior Programmer Analyst | Software Engineering Manager | Principal Role
      Jan 2013 - Jan 2021 · 8 yrs 1 mo

      * Led global engineering teams through Agile transformations, delivering high-impact software via optimized Sprints and continuous code reviews. * Strategic partner to leadership, aligning informatics with business vision through steering committees in Bioinformatics and Small Molecule discovery. * Architected and deployed custom discovery platforms using Java, Python, and RESTful middleware for advanced research analytics. * Managed enterprise infrastructure projects, including data center migrations and global rollouts of modern authentication and Java standards. * Expert Lead Engineer in real-time data integration, designing messaging systems with Apache ActiveMQ and Camel for global Cheminformatics warehouses.

  • System Analyst (Consultant at Genentech) at Cydent Inc.
    Jul 2000 - Jul 2001 · 1 yr 1 mo

    Worked as Lead Developer consultant at client site (Genentech, Inc.) on request tracking systems such as LASAR, ATLIMS which employed enterprise Java J2EE application architecture with web UI using MVC frameworks