Sara Cano Crespo, PhD

Clinical & Translational Research | Breast Cancer & Oncology | Rare Diseases | Biomarkers & Drug Discovery | Clinical Trial Operations | Project Management

Greater Barcelona Metropolitan Area

About

# Clinical Trials # Breast cancer # Biotech & pharmaceutical industry # PhD in Biomedicine # R&D project management # Drug Discovery # Oncology # Rare Diseases # Immunology

Experience

  • Clinical Scientific Manager at SOLTI #cancerresearch
    Dec 2024 - Present · 1 yr 7 mos

    •Scientific Leadership: Driving the scientific integrity and strategic vision of clinical trials across oncology programs. • Study Start-Up & Protocol Design: Leading the design and development of clinical trial synopses, protocols, and informed consent forms in collaboration with investigators and stakeholders. •Clinical Trial Oversight: Monitoring progress, coordinating team meetings, maintaining trial registries (e.g., ClinicalTrials.gov), and supporting data analysis and reporting. • Cross-functional Collaboration: Acting as a key liaison between scientific, clinical, and operational teams to ensure seamless trial implementation and execution. • Stakeholder Engagement: Managing communications with internal teams, investigators, KOLs, and pharmaceutical partners to ensure alignment and expert input. • Translational Research: Identifying and integrating translational components within clinical trials, enhancing the scientific value of each study. • Publication Strategy and Scientific Communication: Coordinating study publication plans, contributing to abstract, poster, and manuscript development.

  • Senior R&D Scientist & Clinical Operations Manager at Gain Therapeutics
    Jan 2022 - Dec 2024 · 3 yrs

    • Drug Discovery: Applying comprehensive understanding of drug development processes. • Clinical Trial Operations: Managing and implementing essential documents and operational processes for clinical trials. • Biomarker Selection: Identifying the most relevant biomarkers for use in clinical settings. • Clinical Data Analysis: Leading comprehensive data analysis from clinical trials. • Leading multidisciplinary international projects in the fields of oncology and rare diseases. • Designing comprehensive preclinical studies and analysis for effective translation into clinical applications. • Managing Collaborations with CRO, KOLs and other stakeholders: Orchestrating integration of diverse research initiatives. • Project Management: Overseeing the efficient execution and coordination of complex research projects, ensuring timely deliverables and optimal team performance.

  • Preclinical Development Scientist at Incyte
    Sep 2020 - Dec 2021 · 1 yr 4 mos

    • Led the design, execution, and analysis of antibody screening in sophisticated in preclinical models. • Project management, including monitoring, evaluating timelines, and overseeing budgets. • Applying extensive knowledge of immunooncology to create advanced in vitro models, including organoids and dynamic tumor microenvironment systems.

  • IRB Barcelona (Full-time · 7 yrs 4 mos)
    • Postdoctoral Researcher
      Jul 2019 - Dec 2021 · 2 yrs 6 mos

      • Oncology Research: Investigating resistance in metastatic colorectal tumors to chemotherapy. • Preclinical Models: Developing advanced models to study cancer progression and treatment efficacy. • Experimental Design and Analysis: Creating, analyzing, and presenting findings from studies. • Utilized mouse models and organoids in experimental research. • Research Consulting: Offering expert guidance on research strategies and methodologies. • Published Research: Author of one scientific publication. • Postdoctoral Research Fellow at Dr. Eduard Batlle's Research Group, Colorectal Cancer Lab.

    • PHD Student
      Sep 2014 - Jul 2019 · 4 yrs 11 mos

      • Cancer Metabolism Research: Exploring cancer as a metabolic disorder. • Amino Acid Transport Expertise: Specializing in the intricacies of amino acid transport. • Proficient in Biochemical & Molecular Biology Techniques: - TECHNIQUES FOR PROTEIN ANALYSIS: Immunobloting , Immunofluorescence, co-immunoprecipitation assays, radioactiveprotein-labelling techniques, SUnSET methodology. - NUCLEIC ACID METHODS: DNA/RNA purification, Polymerase Chain Reaction (PCR), Quantitative real-time PCR (RT-PCR), cloning techniques, gene editing techniques (viral vectors, The PiggyBac Transposon System, CRISPR/Cas9), methods for assessing mitochondrial quality and function, ribosome profiling , tRNA aminoacylation array. - OTHER SPECIFIC TECHNIQUES: Flow citometry, microscopy, ELISA , apoptosis assays, cell cycle analysis, oxidative stress assessment, metabolite transport quantification, oxygen consumption measurements (Seahorse), transcriptomics, metabolomics and PamGene assays. - CELL CULTURE TECHNIQUES • Conducted bioinformatic analysis using tools such as Clone Manager, MEGA, FinchTV, FlowJo, and DNASTAR Laser Gene Software, complemented by statistical analysis proficiency in SPSS Statistics and GraphPad, with a basic programming skill set in R • Published Research: Author of four scientific publications. • Academic Mentorship: Guiding six high school students in their final research projects. • Member of Dr. Manuel Palacín's Research Group, specializing in Amino Acid Transporters and Disease

  • Research And Development Specialist at Merus N.V.
    Aug 2019 - Aug 2020 · 1 yr 1 mo

    • Conducting screening of bispecific antibodies in advanced in vitro models. • Designing, analyzing, conducting and discussing experimental studies in immunooncology. • Project management, including monitoring, evaluating timelines, and overseeing budgets.