Lake County, Illinois, United States
Experienced process engineer with expertise in both drug substance and drug product development across multiple modalities and stages of pipeline development.
R&D Process Engineer for Crystalline Drug Substance and Drug Product Process Development - Developed crystallizations for early pipeline APIs and executed in pilot plant at multiple scale - Engineering lead on multiple oral formulation drug product processes (Bilayer tablets, hot-melt extrusion, and spray drying)
- Developed processes spanning modality (peptide, ADC, oncology) from first GMP delivery to filing. - Led a team of engineers to develop, characterize, and tech transfer processes internally and externally. - Managed scale-up and execution of 3 processes at our pilot plant in a 10-month Ops Engineer rotation. - Coordinated Handler Safety and Industrial Hygiene testing for our small molecule pipeline.
- Optimize reactions and crystallizations to develop commercial manufacturing processes. - Lead departmental intern program for 3 summers, coordinating 15 total intern projects. - Interface and collaborate with colleagues in drug product, analytical, quality, and operations to support both early and late development (from projects at first-in-human studies to supporting a new drug application)
• Optimized a solvent selection guide and performed techno-economic analysis for lignin extraction and valorization in a pulp mill • Developed a high throughput characterization of cellulose accessibility for biomass conversion to sugars
Optimized a potency assay with luciferase reporters for a metabolic and an immuno-oncology target. Designed a nano-luciferase platform assay in two cell lines; directed development with two CROs.
Founded a four-person start-up company that employs non-canonical amino acids in a novel insulin drug. Obtained $20K of funding from investors; directed research in overseas laboratory; filed a provisional patent.