Unterbäch, Valais, Switzerland
Quality services around manufacturing including batch record review, deviation management, qualification of devices and project management
Censo Biotechnologies provides induced pluripotent stem (iPS) cells for research purposes. My project focused on the derivation of human and dog iPS cells for disease modeling. Cell culture techniques in clean room conditions played a central role during the internship. Techniques: • Primary cell reprogramming by episomal DNA, Sendai-viral or mRNA transfection • Handling of iPS cells: Reprogramming, expansion, and cryopreservation • Documentation in protocols and with LIMS software
I applied analytic methods to help in monitoring the manufacturing of biopharmaceuticals. My responsibility was the analysis of biologic concentration and host cell proteins in samples. I worked reliably and accurately in the fast-paced lab environment and coordinated time-sensitive tasks with team members.
From August 2014 to February 2015, I joined the Fraunhofer CMI to investigate Lab-on-a-Chip technology for structural proteomics. The placement required excellent communication and problem-solving abilities. In the highly technical, interdisciplinary environment I established several milestones and long-anticipated progress. Achievements: • I established an enzymatic assay that verified protein transport in a microfluidic system • I recorded the electrokinetic potential of particles with a highly sensitive sensor array • I designed an epifluorescent live staining procedure for cells on the chip