Utrecht, Utrecht, Netherlands
My main PhD project: the international (6 countries) multi-center (15 centra) ImmunoSABR phase 2 trial. (http://www.immunosabr.org) IMMUNOSABR is geared towards opening up a new paradigm in treating metastatic cancer by obtaining clinical proof of concept for a novel bi- and tri-modal curative treatment strategy. High precision stereotactic ablative radiotherapy (SABR) is combined with immunotherapy to form a powerful synergistic anti-tumour strategy. The approach relies on the direct cytotoxic effect of SABR, the abscopal effect of radiation observed at distance from the irradiated metastatic site(s), and the effect of the tumour-specific immunocytokine L19-IL2 and in some cases combined with well-known pembrolizumab.
Main responsible for Pharmacovigilance - managing and reporting ICSR clinical trial(s) for Maastricht University