Cambridge, England, United Kingdom
PhD student funded by the Wellcome Trust on the integrative cell mechanisms (iCM) program. Supervised by Dr. Matthew Swaffer and Professor Sander Granneman. Aim to integrate metabolic labelling, transcriptomics and proteomics approaches to investigate how the association between RNA and proteins changes as cell size increases, as well as implications for cellular physiology regarding stress and breakdown of biosynthetic scaling.
I mentor students taking A level Mathematics with this subject
Investigated autophagy initiation in human kidney cells. In particular, I optimised the inhibition of autophagy using an ULK1 inhibitor and a TBK1 inhibitor. I performed literature research to find the most suitable inhibitors and antibodies. I also expressed and purified two proteins for in vitro assays. Delivered a presentation for the research group at the end of the placement.
My team was allocated a project to assess whether their business model would do well in the market, and to give our opinions on their future directions, (e.g. specialise or stay generalists)