Roermond, Limburg, Netherlands
I am a pharmaceutical professional with more than 13 years of experience in chemical development, including 5 years in project and team leadership roles. My expertise lies in process development and GMP manufacturing of APIs, supporting drug development programs from early development to clinical supply. I have extensive experience working in cross-functional environments, coordinating chemists, analysts, engineers, and manufacturing teams to deliver complex development projects. Key areas of expertise include: • API process development and optimization • GMP manufacturing and regulatory compliance • CMC project management • Process scale-up and technology transfer • Cross-functional team leadership
Chemical Project Leader of a process R&D team. Optimization and development of a synthetic chemical process for GMP and/or non-GMP production of an API in the Pilot Plant.
Synthesis of heterocyclic compounds with potential anticancer activity as intercalating agents. 1D-proton NMR analysis, organic synthesis
Asymmetric synthesis of conformationally constrained gamma-amino acids derivatives, as building blocks in the design of new Neuropeptide Y analogues by solid phase peptide synthesis, in order to analyze their conformation and test their activity. 1D- and 2D-proton NMR (Nuclear Magnetic Resonance) analysis, purification of peptides by HPLC (High Performance Liquid Chormatography) preparative, CD (Circular Dichroism) analysis, Drug Design.
Organic synthesis of different compounds for pharmaceutical industries. Process and Development, Discovery Chemistry
Organic synthesis of different compounds for pharmaceutical industries. Preparation of known and unknown compounds from small to medium scale.