Paris, Île-de-France, France
Driven and detail-oriented scientist with industry experience in structure-based drug design, cheminformatics, and early-stage AI/ML integration. Passionate about combining molecular modeling and ML to accelerate therapeutic design and make a meaningful impact on human health. Specialties: computer-aided drug design (docking, molecular dynamics, DFT), cheminformatics, public speaking, science communication, organic chemistry, photopharmacology. Email: [email protected]; Twitter: @pierkoba ResearchGate: https://www.researchgate.net/profile/Piermichele-Kobauri
Aqemia is a next-gen pharmatech company generating one of the world's fastest-growing drug discovery pipeline. Our mission is to design fast innovative drug candidates for dozens of critical diseases. Our differentiation lies in our unique quantum and statistical mechanics algorithms fueling a generative artificial intelligence to design novel drug candidates. The disruptive speed and accuracy of our technological platform enables us to scale drug discovery projects just like tech projects. As a Drug Hunter, I’m in charge of identifying drug candidates to cure major diseases. To do that, within an interdisciplinary team made up of medicinal chemists, physicists and machine learning engineers, I identify active molecules of interest using our drug-target affinity and property prediction pipeline and I leverage groundbreaking, disruptive algorithms.
PhD Thesis title: "Rational drug design in photopharmacology". Mentors: Prof. Ben L. Feringa, Prof. Wiktor Szymanski - Docking, QM and MD to design and rationalize light-controlled biological tools - Design, synthesis, purification, analysis and photochemical/biological evaluation of photoswitchable antibiotics and chemotherapeutic agents - Collaborations with scientists from different fields (biochemists, microbiologists)
Erasmus+ Internship. Supervisors: Prof. Bente Frølund, Prof. Marco Lucio Lolli - Synthesis, purification and characterization of non-aromatic heterocylic analogs of GABA
Internship at MEDSynth. - Applied pharmacophore modeling to drug repurposing against Leishmaniasis - Synthesis, purification and characaterization of heteorcyclic compounds with anti-Leishmanial activity
Personal assistant to the Educational supervisor of the Chemistry Department. - Planned lectures and managed booking of lecture rooms - Posted regular updates on the website, and inserted data about exams