Philipp Anstaett-Pfeifer

Commercial Strategy & Launch Leader | Rare Disease | Alliance & International Expansion | PhD + MBA

Zurich, Zurich, Switzerland

About

Commercial strategy and launch leader in rare disease and advanced therapies, with a track record of scaling international operations, enabling market expansion, and translating complex science into sustainable commercial performance. Over the past decade, I have operated at the intersection of science, strategy, and execution — building the governance, analytics, and cross-functional alignment required to successfully launch and scale therapies across Europe and Asia. At Mirum Pharmaceuticals, I currently lead international commercial operations, overseeing launch readiness, product and launch governance, competitive intelligence, alliance commercial management, and market analytics. I have coordinated 15+ international launches, supported reimbursement success in multiple markets, built integrated launch-readiness frameworks, and enabled alliance-driven expansion in Asia. My work has directly supported revenue growth, strategic prioritization, and long-range brand planning. Beyond execution, I focus on systems-building: - Designing scalable launch and performance governance structures - Translating market research and demand studies into strategic brand decisions - Leading alliance commercial negotiations and financial analyses - Building cross-functional alignment across commercial, medical, clinical, finance, and supply chain - Developing teams and coaching emerging leaders Earlier in my career, I worked in business development and R&D leadership roles, combining scientific depth (PhD in Chemical & Molecular Sciences) with commercial training (MBA, University of St. Gallen). This dual perspective allows me to evaluate assets from both development and go-to-market lenses and to bridge strategic intent with operational reality. I am particularly motivated by scaling innovative therapies in rare and specialty diseases — where thoughtful launch strategy, stakeholder alignment, and disciplined execution meaningfully impact patient access.

Experience

  • Mirum Pharmaceuticals, Inc. (Zug, Switzerland)
    • Director Commercial Operations
      Jul 2024 - Present · 2 yrs 1 mo

      Commercial operations, focused on preparation and execution of launches (assets, indications) as well as business case assessments for go-to-market decision and model. Leadership of extensive cross-functional team (~25 people). Commercial insights and analytics, focused on market research and competitive intelligence, pre-launch and lifecycle management phases ranging from scientific to sales analyses. Market research: sales analytics, Awareness Trial and Usage (ATU) study, patient journey, demand study. Competitive intelligence: field insights, leading scientific and promotional dissemination of conferences, insights from new scientific publications, press releases, earnings / investor calls. Strategic alliance management (out-licensing partnership): lead for alliance relationships and commercial aspects for Japan, Greater China, South Korea.

    • Associate Director, Commercial Operations
      Feb 2024 - Jun 2024 · 5 mos

    • Associate Director, International Program Management
      Jan 2022 - Jan 2024 · 2 yrs 1 mo

      Main responsibilities: - Launch readiness for international markets - Launch performance in core European markets - management of alliance partnerships in Asia - competitive intelligence insight generation for international markets

  • bluebird bio (Full-time · 2 yrs 1 mo)
    • Senior Manager Business Operations
      Jun 2021 - Dec 2021 · 7 mos

      Treatment center engagement lead. Business operations strategy EU. - Leading workstream to customize business operations strategy, activities and materials in preparation for a gene therapy product launch in a new therapeutic area for the company; represented the operational organization in cross-functional brand team - Assessing capacity of treatment centers with consultant support, optimizing treatment center network and market entry strategy - Evaluating patient demand and treatment capacity for sales & operating planning (S&OP) - Acting as prime point of contact for CMO, ensuring alignment with internal manufacturing and supply chain functions - Developed lean digital tracking and reporting system, ensuring projects remain in time & on budget and internal alignment on changes is retained - Designed and held workshop to optimize approach to virtual, hybrid and on-site engagements for customer facing European functions upon lift of COVID-19 measures - Represented EU interests in development and roll-out of global contract management program

    • Manager Commercial Operations Europe
      Dec 2019 - May 2021 · 1 yr 6 mos

      Treatment center engagement lead. - Managed cross-functional, geographically dispersed teams, including commercial, legal, medical, IT and technical operations functions, to launch gene therapies in qualified treatment centers in several European countries, incl. Germany, UK, Greece, Denmark - Established strong rapport with key opinion leaders and top hospital management across top EU markets, forming strong trust and relations - Negotiated master service agreements with hospitals in close collaboration with data privacy and legal, providing compliant partnership contracts - Streamlined formal internal decision-making processes, reducing internal turn-around time in contract negotiations by 75% - Organized EU-wide meeting to train and update staff on treatment center engagement - Formulated and aligned first response strategy to adapt operations to new COVID-19 environment

  • ChromaCon AG (Zürich Area, Switzerland)
    • Business Director
      May 2017 - Nov 2019 · 2 yrs 7 mos

      Business Development & Licensing - Sourced and evaluated external partners for specific R&D problems, acquiring new programs and starting internal integration - Scouted for partnering and out-licensing of own assets to bigger biotech - Assessed internal R&D projects with risk adjusted NPV methods, translating R&D projects into financially valued M&A assets - Divested programs after shift in strategic direction, terminating operative collaborations and settling IP questions Marketing & Sales - Led relaunch of main website and adjustment of newsletters and social media marketing, supporting expansion to new market segment - Analyzed regional sales channel performances, providing the CEO with insights and improvement plans - Managed expanding network of distributors in Europe, North America and Asia, providing international foothold with lean own resources - Established a concise customer and partner relationship management, decreasing response times by 50% - Post-M&A integration of own marketing function into the global operations of the acquirer

    • Head Of Development
      Jul 2015 - May 2017 · 1 yr 11 mos

      Management of internal R&D and of external R&D collaborations (immuno-oncology therapeutics, affinity reagents). - Managed publicly co-funded R&D projects for reagent and drug development (immuno-checkpoint inhibitors) - Coordinated activities with international network of academic and industrial partners, resulting in new IP - Discussed in-licensing opportunities and term sheets with academic partners, securing development rights - Sourced and evaluated external partners for specific R&D problems, expanding the portfolio with joint projects

  • University of Zurich (4 yrs 3 mos)
    • Postdoctoral Fellow
      Oct 2014 - Jun 2015 · 9 mos

      Continuation of research activities, with increased independence and responsibility. Moreover: - Peer-reviewed articles and grant applications as community service

    • Research and Teaching Assistant
      Apr 2011 - Sep 2014 · 3 yrs 6 mos

      PhD student in the group of Prof. Gilles Gasser. - Researched in chemical biology, leading to 10 publications in scientific journals and books (see publication section below) - Presented at international conferences, e.g. in China and France, resulting in subsequent collaborations - Management of research projects - Responsibility for purchase of lab equipment and consumables - Supervision and guidance of students during their Master’s thesis and in lab courses - Additional training courses, including patent law

  • Visiting Researcher at Monash University
    Jul 2012 - Sep 2012 · 3 mos

    Project lead for R&D cooperation in the field of bio-nanotechnology, between the research group of Prof. Udo Bach (Monash University) and Prof. Gilles Gasser (University of Zurich). - Headed team from Zurich and Melbourne in bio-nanotechnology project, resulting in a high-impact publication and award-winning presentation