Vienna, Vienna, Austria
My passion is to integrate advanced biochemical, biophysical, and cellular assays into state-of-the-art drug discovery workflows. My strong background in systems biology, programming, and statistics enables me to lead a highly multidisciplinary team of researchers to detect biological relevance amongst the many hypotheses we test every day. As head of High-Throughput Biology here at BI, I have guided numerous projects from exploratory feeder stages to clinical candidate selection. During my career, I have co-authored multiple peer reviewed journal articles and book chapters, have written successful grant applications, and contributed to several patent applications. I have over 15 years of research and 7 years of start-up and industry experience and am well versed in leading successful teams of 25+ people in challenging and fast-paced environments. I thrive on accelerating R&D efforts and translating them into reliable discovery pipelines for pre-clinical and pre-production processes.
• Leading a team of 25+ in High-Throughput Biology focused on early-stage drug discovery in Oncology. • Managing Biochemical, Biophysical, and Cellular Assay Labs to streamline assay development and deployment. • AI-Readiness: Assay Integration Lab, ensuring effective curation of internal and external data sources.
• Leading four cellular assays labs as an interim team lead, ensuring seamless support for the entire TA portfolio. • Collaborating with cross-functional teams to enhance laboratory processes and operational efficiency. • Fostering a culture of innovation and teamwork, driving engagement and productivity among lab personnel and across sites.
Group Leader for High-Throughput Biology in Oncology, managing the Biochemical, Biophysical, and Cellular Assay Labs for early-stage drug discovery, as well as the Assay Integration Lab for curation of internal and external data sources.
* High-throughput platform development for multi-cycle chemical and enzymatic reactions * Optimization of enzyme activities for peptide and oligo manipulation * Design of complex hybrid peptide-oligo architectures * Baselining, process & quality control, assay stabilization, multivariate data analysis * Core Team Lead
* Planning and implementation of robotics and automation solutions to enable scale-up * Optimization of bench-top assay biochemistry into a push-button-go high-throughput system
* SBIR-funded start-up founder with patent, incubator, and pitching experience * High-throughput screening and drug discovery through small molecule characterization, phenotyping, and machine learning in a yeast model system
* Development of a phenotype screening platform for yeast genetic interaction screening * Model systems and bioinformatics tools for epigenetics and systems biology of aging and cancer * Plasma proteomic and integrative data analysis pipeline for Alzheimer's Disease and other dementias
* High-content plasma proteomics and biomarker discovery in neurodegenerative diseases * Antibody-based assay development for plasma proteomics in mice and humans * Molecular dissection of the role of Autophagy in Alzheimer's Disease