Peter McLean

Scientific Director, Gastroenterology Drug Discovery Unit at Takeda Pharmaceuticals

Lausanne, Vaud, Switzerland

About

Translational scientist with experience of preclinical and clinical research in academia, drug discovery and nutrition health sciences. Expertise in gastroenterology, mucosal immunology and microbiome. Project management/leadership and line management experience. Co-ordination of external collaborations/partnerships/alliances. Strong experience in search, evaluation and business development. Strong publication track record with a total of 45+ publications over the last 15 years Specialties: - translational sciences - gastrointestinal and digestive health - microbiome - immunology, inflammation - neurology, pain, behavior - nutrition health sciences - pharmacology, drug discovery

Experience

  • Scientific Director, Gastroenterology Drug Discovery Unit at Takeda Pharmaceuticals
    Nov 2014 - Present · 11 yrs 9 mos

    Research leader responsible for providing the EU components of the global strategy for GI research contributing to development of the preclinical and early clinical pipeline. Co-ordinating global microbiome research activities for GI diseases. Leading projects investigating mechanisms of GI mucosal biology, neurogastroenterology and the microbiome.

  • Senior R&D specialist, Nestle Research at Nestlé
    Mar 2009 - Nov 2014 · 5 yrs 9 mos

    Clinical and pre-clinical project leader employing translational science technologies in the development of bioactive/functional ingredients in preclinical and early clinical efficacy studies of GI diseases; including analyses of interventions targeting the microbiome.

  • GlaxoSmithKline (7 yrs 3 mos)
    • Head Translational Biology Group, Immuno-Inflammation CEDD
      Sep 2006 - Mar 2009 · 2 yrs 7 mos

      Project Leader and Head, Translational Biology group responsible for : 1) drug target identification and target validation 2) profiling biological activity of drug candidates in native tissue assays and disease models 3) development of translational biomarkers 4) development and operation of PK-PD assays to support lead optimisation and dose selection

    • Team Leader, Gastro-Intestinal Research Department
      2004 - 2007 · 3 yrs

      Project leader and Team leader responsible for development and operation of assays supporting: 1) drug target identification and target validation 2) profiling biological activity of hits, leads and drug candidates 3) PK-PD analyses

    • Investigator, Neurology and Gastro-Intestinal Diseases CEDD
      2002 - 2004 · 2 yrs

      Project leader and hands on operation of assays supporting: 1) drug target identification and target validation 2) profiling biological activity of hits, leads and drug candidates 3) PK-PD analyses

  • Royal Society Fellowship and Lecturer at William Harvey Research Institute, Queen Mary University London
    2000 - Jan 2002 · 2 yrs 1 mo

    Immunology/Cardiovascular physiology and pharmacology

  • British Heart Foundation Research Fellow at University College London
    1998 - 2000 · 2 yrs

    Immunology/Cardiovascular physiology and pharmacology