Greater Strasbourg Metropolitan Area
I have more than 20 years of experience in the development of biologically active molecules, natural products (antibiotics) and analytics. I have a PhD in Biological Chemistry with a focus on the isolation and characterisation of antibiotics from unexplored natural sources. As a team leader in pharmaceutical and biotech companies for 10 years, I developed lipid nanoparticles that are now widely used in RNA vaccines. As a research fellow in academia, I worked on antiviral compounds and coordinated several projects in cell biology and cancer research, developing a wealth of new analytical methods. I enjoy working with interdisciplinary teams, solving problems and bringing people together through efficient reporting. Strict adherence to quality control throughout the process has always been key to the reproducibility of my scientific results in ISO certified environments. As a speaker I have represented the team in the scientific community at international symposia. I've recently joined EDQM, where I'm currently working as a scientific editor, ensuring the quality of texts published in the Pharmacopoeia.
Scientific editor in the European Pharmacopoeia department (EPD): reviewing and editing of official texts
Development of Antibody-drug conjugated Nanomaterials
• Project management in the R&D of bioactive nano-materials • Organic synthesis of amphiphilic compounds • Multi-step synthesis of antiviral and anti-inflammatory compound • Biological data analysis (from in vitro and in vivo experiments) • Design of biological tests on cancer cell lines • Bioproduction and transfection (gene and RNA delivery) • Biophysical characterization • Supervision of a thesis student and trainees • Writing of patents, and publication of the research in international journals • Writing applications for grants
• Management of chemistry services (polymers ; amphiphilic cationic lipids) • Project management, team leader (trainees, technicians) • Coordination between the various departments of the company (biology team, production team), interaction with the industrial property and marketing department • Quality control and respect of ISO norms in production • Expertise in organic and polymer chemistry • Design and development of new bioactive molecules for bio-delivery • Follow up from laboratory scale to commercialized products • Patent writing, and representation in the scientific community • Participation in the securing of Industrial Property
• Technology transfer from University to the « start-up » company • Isolation and identification of antimicrobial compounds from natural resources • Organic synthesis of new pharmacologically active molecules and analogues