Basel, Basel, Switzerland
Lab technician (swiss dipl.) with more than 17 years’ experience in drug development and radiochemical analysis within the pharmaceutical industry. I have an extended knowledge in a broad field of analytical and purification techniques and developed myself to a HPLC and purification expert, worked also under GMP. Straightforward thinking. Persistent when problems coming up or new task have to be done or implemented, therefore finding productive and pragmatic solutions. Passion for laboratory work and lab science. Quick perceptive comprehension. Respected by the group as a cooperative team player with good communication skills. Goal oriented, used to deliver within short timelines without compromising on quality. Open and willing to learn new things. Good IT and software skills. Passion for laboratory bench work.
Analytical Developement Group (AD) Analysis and methode development of large molecules using chemical and physical testing methods. HPLC and UPLC: Plattform Method Evaluation, Method transfer and implementation for SEC, IEX, RP. HPLC expert. Validation of developed HPLC methods. Reporting, Data Review, Empower Power user. CE, iCief
Lab technician in Bioanalytics group : protein and large molecul HPLC analysis according cGMP guidelines.(Ph.Eur, USP, ICH guidelines etc). Core team member which means responsible person for planing, execution, delegation or performing of analytical bench work as well as writing reports and SOPs in the area of HPLC analysis . Strong personal soft skills. Customer oriented, delivery of high quality results within given time lines. Methode transfer, methode setup, validation of HPLC methodes in the area of proteins analysis f.e.g. SEC, CEX, RP-HPLC, UHPLC. MONO Sacharide characterirazition, Peptide mapping. Contribution to SOP'S and reports. Interpretation of results, ooe or oos handling.
Analytical: •HPLC, MS, CE, titration, KF, UV, Liquid Scintillation Counting (LSC), Proteinanalysis (SEC, UV-DAR, CE) Synthesis : •Purification techniques like semi-preparative and preparative HPLC, SFC, salt formation, crystallization, flash chromatography GMP: •HPLC (radiolabeled DS/DP) method development , method validation and release analysis including reporting of results and data. Building up GMP lab including qualification of new and existing equipment. Preparation of associated qualification documents, schedule and perform routine maintenance of instruments Biological : •CE, gel electrophoresis, plasmid amplification, PCR, workup of RNA (Extraction) analysis of oligonucleotides, synthesis (PCR) and purification of RNA, end labeling with radioactive 32P and 35S Computing: •MS Word/Office (Using and writing of Excel templates to simplify processes and calculations), Chromeleon, Agilent Open Lab/Chemstation, Radiostar, Xcalibur ,Waters Masslynx, Easy Stat, SAP, Biobook (E-Notebook), databases e.g. Glims, Tedi/Predi, IMS, Photoshop, Joomla Webpages General • Keep record of chemicals, intermediates, excipients and solvents within own area of responsibility. • ordering of lab equipement and spare material within analytic group • radiosaftey responsible person in analytic group
ISOTOPE Analytics. Providing DS for human ADME studies. purification, dilution, quantification od radio labeled DS and DP. Methode development, chiral HPLC, RP, Preparative purification techniques using HPLC, mass triggered HPLC, small and large scale purification. Everything under radio protection rules. Environmental measurements.
Isotope Chemistry. Analysis and purification of radio labeled DS for research and development. Contributing to DMPK studies. HPLC, MS, salt formationen, prep HPLC., Radio protection
Produktionsanalytik Labor, Inprozess und Endproduktkontrolle für Textilfarbstoffproduktion. Schichtführer. HPLC, Titrationen, UV, Spektroskopie, DC anlalytical lab in production , inprocess controll of reactions in production, UV Spectroscopy, HPLC, Tritations, DC, Karl Fischer