Eindhoven, North Brabant, Netherlands
I am an enthusiastic and dedicated chemist with a broad experience in organic chemistry and medicinal chemistry within an international R&D organisation. Communication, organisation, presentation, team work and creativity are my strongest skills. At Merck (MSD/Organon) I worked with lots of enthusiasm in several multidisciplinary research teams, developing potential new drugs. Recent courses • Six Sigma – Green belt (Maruna, process improvement) - February 2012 • Current Good Manufacturing Practice (middenkader Pharma, PCS) - March 2012 . Specialties: - Medicinal Chemistry - Nuclear receptors - GPCRs - Synthetic Organic Chemistry - Lead optimisation - Multi disciplinary teamwork - Coaching - Communication - Ability to motivate - Innovative problem solving - Recruitment of HLO chemists
Responsible for all organic chemistry and medicinal chemistry aspects of research projects towards lead finding and lead optimization. This encompasses amongst others, determination of structure–property relations regarding potency, selectivity, pharmacokinetics and toxicology. Based on these data, I was responsible for a team designing new chemical entities and the synthetic routes towards them. Daily interdisciplinary contact within project teams, frequently in English. I was an active participant in a number of teams, providing leadership, mediation and organization when needed. Managerial experience. As a group leader I have managed/coached numerous organic chemists (BSc.) with a broad range of experiences. Coaching via open communication enhanced motivation and performance of co-workers with benefits in creativity and output. My team leadership skills were recognised enough that under-performing co-workers were placed in my group to improve their functioning. Responsible for the recruitment of new employees and trainees (BSc., organic chemists)(2003- June 2011) Headed departmental recruitment team. Initiated and maintained contacts with schools for organic chemists. This included organising excursions, presenting lectures, visiting exhibitions as well as interaction with teachers and trainee coordinators on an informal level. As a result, a broad range of potential new co-workers and trainees were recruited to the departments of Medicinal Chemistry and Process Development.
Responsible for the design of new synthetic routes and the synthesis of new chemical entities. Purification and analysis of obtained products using NMR, LC-MS, HPLC. Beside solution phase chemistry also experience with solid phase chemistry (see publications), combichem and parallel synthesis. Posted for six weeks at Pharmacopeia, Princeton (USA) as part of a collaboration on solid phase chemistry.