San Francisco, California, United States
Principal Computational Scientist with 10+ years of experience spanning academia, non-profit research, and industry. Specialized in single-cell and multi-omic analysis, neuroscience, and disease biology, with a strong publication record in top-tier journals. Known for translating complex biological data into rigorous, impactful insights and for leading collaborative, fast-paced research efforts.
Led single-cell RNA-seq analysis for multiple large-scale, multi-institutional studies of brain cell types as part of the NIH BRAIN Initiative Cell Census Network (BICCN). First-authored high-impact publications that established widely adopted brain cell-type nomenclature and methods, shaping current understanding of human brain cellular composition. Owned development and implementation of QC frameworks and scalable analysis pipelines for single-cell and multi-omic data, improving rigor, reproducibility, and cross-study comparability. Collaborated closely with academic and industry partners to deploy machine learning-enabled tools, reference atlases, and visualization platforms. Served as a scientific communicator and technical leader, presenting regularly to institute leadership, NIH, and external collaborators, and leading a weekly bioinformatics working group.
Doctoral research in retinal neuroregeneration, systems biology, and translational neuroscience. -Conducted independent PhD research on in vivo regeneration of retinal neurons in adult mammalian models, advancing understanding of mechanisms relevant to neurodegenerative disease and regenerative medicine. -Analyzed and integrated large-scale multi-omics datasets (epigenomic, transcriptomic, proteomic) to investigate disease mechanisms, biomarkers, and candidate therapeutic targets. -Collaborated extensively across disciplines including electrophysiology, microscopy, and single-cell transcriptomics to generate convergent biological evidence. -Mentored junior trainees and successfully sourced grants and fellowships, developing strong foundations in scientific leadership, communication, and funding strategy.
Clinical research operations and human tissue programs -Played a critical operational role in human neuropathology research, supporting Alzheimer’s and Parkinson’s disease programs through precise brain removal and anatomical dissection. -Ensured high-quality tissue processing and structural annotation, enabling downstream molecular, histological analyses.
Neurodegeneration, imaging, and computational methods -Designed and implemented automated image-analysis pipelines for electron and confocal microscopy, improving scalability, reproducibility, and quantitative rigor. -Contributed as a scientific collaborator and co-author on multiple interdisciplinary research projects spanning neurodegenerative disease mechanisms. -Led day-to-day mentoring and performance management for a team of five junior researchers, balancing delivery, skill development, and scientific quality. -Focused on Alzheimer’s, Parkinson’s, and related neurodegenerative disorders, building a strong foundation in neuroscience and disease-oriented research strategy.