Nicolas Dreyfus

Principal Scientist, Medicinal Chemistry at AC Immune

Lausanne Metropolitan Area

About

I am an experienced and creative Senior Research Scientist with a passion for Drug Discovery and its associated challenges. I have applied my drug design and medicinal chemistry expertise on areas such as pain, neurodegenerative diseases, oncology and PET ligands. I have demonstrated effective project leadership collaborating with cross-functional partners in toxicology, formulation, biology and legal departments. With a thorough understanding of data analysis tools and ADME principles, I have a proven track record of delivering candidates molecules and patent publications.

Experience

  • AC Immune (Lausanne, Vaud, Switzerland)
    • Principal Scientist, Medicinal Chemistry
      Mar 2023 - Present · 3 yrs 4 mos

    • Senior Scientist
      Aug 2020 - Mar 2023 · 2 yrs 8 mos

  • Eli Lilly and Company (20 yrs 10 mos)
    • Senior Research Scientist
      Oct 2016 - Aug 2020 · 3 yrs 11 mos

      Lead Chemist for Pain project in early Hit to Lead phase Supervision of a team of 2 chemists and collaboration with team of synthetic chemists in Asia

    • Research Scientist
      Oct 2009 - Oct 2016 · 7 yrs 1 mo

      Design and discovery of small molecules to deliver clinical candidate for Neurodegenerative Disease. In charge of team of 2-5 research chemists. Developed strong knowledge of DMPK and Toxicology principles whilst bringing new chemical entities through the flowscheme. Worked in both Target to Hit and Hit to Candidate phases.

    • Research Chemist
      Oct 2004 - Oct 2009 · 5 yrs 1 mo