Greater Paris Metropolitan Region
• Leading digitalization and transformation of drug discovery through the deployment of AI- and data-driven solutions for Research • Strong technical expertise in computational chemistry at the service of drug discovery projects within interdisciplinary teams • Excellent people leader skills in an international and hybrid context • Eager-to-learn mindset. Passionate about innovation and efficiency. Committed to fostering a culture of trust.
Leading the deployment of data- and AI-driven tools for Research within the IT department, and contributing to the broader Data & AI strategy for Research.
Lead a group of 9 computational chemists in 2 teams + 3-5 consultants: - Ensure timely application of relevant state-of-the-art modeling methods to drug discovery projects, fostering mutual understanding and efficient collaboration with medicinal chemists - Steer development and implementation of new algorithms to address critical issues faced during compound optimization (including Machine Learning models and Generative AI) - Built a performant and close-knit group with a culture of trust, transparency and mutual support - Part of the management committee overseeing project advancement and strategy Co-lead transformation of Research informatics infrastructure to generate, collect, combine and serve drug discovery data to project teams: - Define implementation strategy as part of the Program Management Team (including introduction of ontology) - Follow-up on implementation as Product Owner in an agile Scrum team (oversee 7 developers, analysts, architects) - Supervise maintenance, development and user training for three key discovery informatics systems Operational Site Head for Romainville site (France): - Organise local operations to maximize site performance - Align accross sites for a one-company approach
- Coordination of a French collaborative project with one academic and two industrial partners - Setup of molecular modelling infrastructure and creation of corporate database for compounds and experimental results - Support to medicinal chemistry projects
- Molecular modelling support to lead finding and optimization projects (fungicides) - Quantum chemistry calculations, comparison of virtual screening methodologies
- Project: “Conception and synthesis of protein kinase CK2 inhibitors” - Organic synthesis, docking, virtual screening, development of scoring functions