Utrecht, Utrecht, Netherlands
As a PhD candidate, I am building up experience in patient-oriented research in two research programs. • SYMPHONY (https://symphonyconsortium.nl/): This consortium aims to improve treatment for patients with bleeding disorders. I investigate blood platelet disorders with functional cell biology, proteomics and genetics. • Public-private research collaboration. Preclinical proof-of-concept studies to support the development of a new hemostatic agent (https://tinyurl.com/ywrnxj76). Presentations/posters: 2024 DHC Papendal 2023 ISTH Montréal 2023 NVTH Koudekerke (2x) https://tinyurl.com/4xx87e6f 2023 BSHT Birmingham https://tinyurl.com/bddxwvm4 2023 EAHAD Manchester PO296 https://onlinelibrary.wiley.com/doi/10.1111/hae.14715 2022 ISTH London PB0719 https://www.eventscribe.net/2022/program/searchGlobal.asp
Exploring novel therapeutics for inherited bleeding disorders
Thesis title: Advanced diagnostics and novel therapeutics for platelet function disorders. Defense date: 22-05-2025
Minor Research Project at the department of Pathology. Project titles: • The effect of hypertension on the cerebral microvasculature. • The crucial role of S100A8/A9 (calprotectin) in liver ischemia/reperfusion injury. Techniques: immunohistochemistry, histological staining, immunofluorescence, image analysis (ImageJ, Leica Application Suite), tissue sectioning (para/cryo), RNA isolation, RT-qPCR
Studying interactions between contact activation and the fibrinolytic system in human inflammatory pathology.