Michael David Brügger

Team Leader Discovery Biology with Dimericon Therapeutics

Zürich Metropolitan Area

About

Experience

  • Team Leader Discovery Biology at Dimericon Therapeutics
    Oct 2025 - Present · 10 mos

  • Research Scientist at Dimericon Therapeutics
    Sep 2024 - Sep 2025 · 1 yr 1 mo

  • University of Zurich (Zurich, Switzerland)
    • Postdoctoral Researcher
      Jun 2023 - Jul 2024 · 1 yr 2 mos

      Basler Lab, Department of Molecular Life Sciences, University of Zürich • Established in vitro models to investigate the crosstalk between intestinal epithelial and stromal cells (intestinal assembloids, iPSC/ESC derived intestinal organoids)

    • Laboratory Technician
      Nov 2020 - Jul 2024 · 3 yrs 9 mos

      Life Science Zürich Learning Center, University of Zürich • Maintenance, sales & shipping (incl. customer stupport) of D. melanogaster (fruit fly) stocks • Preparation of courses for highschool students (Genetics, Mendelian Inheritance

    • Doctoral Researcher
      Jun 2018 - May 2023 · 5 yrs

      Basler Lab, Department of Molecular Life Sciences, University of Zürich • Generated a single-cell transcriptomic atlas of the developing and adult (healthy and inflamed) murine colon and validated cell populations in vivo. • Designed and established a novel murine colorectal cancer model to study perturbations of the tumour microenvironment using colonoscopy-guided orthotopic transplantation of colonic organoids harbouring oncogenic mutations and cell-penetrating peptides. • Presented scientific progress at group/department meetings and international conferences. • Published papers in peer-reviewed journals and wrote multiple grant applications. • Mentored summer and master students and conceptualised/taught courses to bachelor students.

  • Research Assistant at ETH Zürich
    Aug 2016 - Apr 2018 · 1 yr 9 mos

    Stocker Lab, Institute of Molecular Systems Biology, ETH Zürich • Generated transgenic fly lines to study the WNK signalling pathway using site-directed mutagenesis. • Assisted in teaching undergraduate practical course in genetics.