Myrtle Beach, South Carolina, United States
• Investigated the role of endogenous nicotinic acetylcholine receptor modulators in the development of neocortical circuits and visual cortical plasticity. • Assessed endophenotypes of psychiatric disorders in mice through a battery of operant-based behavioral tests run using a touch-screen based system. • Designed, developed and characterized tools for cell-type specific over-expression and microRNA mediated knockdown of proteins and probes for double fluorescent in situ hybridization (DISH).
• Investigated the impact of Alzheimer’s disease linked mutations and Alzheimer’s disease related proteins on the development, maturation and viability of adult neural stem cells in mouse models. • Utilized in vivo models and developed or modified several in vitro assays for the assessment of neural stem cell function in disease as well as in response to exogenous drugs or metabolites.