Lausanne, Vaud, Switzerland
Experienced nanomedicine and drug delivery Scientist, Inventor, certified Project Manager and Project Leader focused on pharmaceutical development of Non-Biological Complex Drugs (NBCDs), New Chemical Entities (NCEs) and New Biological Entities (NBEs) to diagnose, treat and prevent neurodegeneration.
Leading AC Immune’s proprietary vaccine technology platform development from CMC standpoint. Currently acting as CMC project leader for AC Immune anti-Abeta vaccine ACI-24.
Leading anti-Amyloid beta vaccine API and Drug Product development In-house and at Contract Manufacturing Organizations to support pre-clinical and clinical phases.
Development of nanoparticle-decorated T cells for blood-brain barrier (BBB) transport • Preparation of reactive nanoparticles for live cell surface functionalization. • Assessment of viability and key cellular functions of nanoparticle-decorated T cells. • Evaluation of nanoparticle-decorated T cells as carrier across in vitro BBB models PhD thesis supervisor: Prof. Dr. Harm-Anton Klok
Master thesis work in Organic synthesis: • Preparation of shape persistent molecules • Development of an NMR characterization approach to determine molecular 3D-conformations. MSc thesis title: Synthesis of novel calixarene derivatives as host molecules for metalofullerenes MSc supervisors: Prof. Dr. François Diederich, Prof. Dr. Yoko Yamakoshi
Drug Formulation & Delivery internship (Group Prof. Leroux) • Synthesis of polymers by control radical polymerization techniques (ATRP). • Preparation of protein-polymer conjugates.
• Synthesis of polyaromatic compounds for application in photovoltaics.