Marcin Grzybowski

PhD / Microbiologist / Drug Discovery Scientist / Animal Research Expert / Team Leader / Open to roles in Clinical Research & Translational Medicine

Warsaw, Mazowieckie, Poland

About

๐ŸŽฏ Open to opportunities where I can apply my skills and mindset in fresh ways โ€“ whether in drug discovery or in new professional areas that value analytical thinking, collaboration and scientific curiosity. ๐Ÿ‘จโ€๐Ÿ”ฌ Iโ€™m a biologist and experienced research scientist with a strong track record in non-clinical oncology, experimental immunology, microbiology and in vivo pharmacology. My professional pathway has been shaped by curiosity, analytical precision and a deep commitment to quality science. ๐Ÿง  My core expertise: โ€” In vivo models of cancer and inflammation, PK/PD studies, biomarker discovery โ€” Molecular biology, microbiology and immunology (including immuno-oncology and vaccine research) โ€” Scientific documentation, regulatory submissions (animal studies), mentoring and training ๐Ÿ’ก Strengths and working style: โ€” Analytical mindset with hands-on experience in biostatistics and data-driven decision making โ€” Structured and detail-oriented approach to research and project execution โ€” Empathetic communicator with a strong team spirit and high reliability under pressure โ€” Independent in my scientific thinking, yet always open to feedback and growth ๐Ÿ“š Scientific track record: โ€” PhD in biology (microbiology & immunology) โ€” First author of 5 original peer-reviewed publications โ€” Co-author of 20+ other scientific papers โ€” Co-inventor on 2 patents related to small-molecule arginase inhibitors โ€” ORCID profile: https://orcid.org/0000-0002-5197-7538 ๐Ÿค I value working in teams driven by clarity, purpose and mutual respect - where I can apply my strengths to meaningful, real-world challenges.

Experience

  • Senior Microbiologist, Quality Control Development at Bacteromic
    Jul 2025 - Present ยท 1 yr 1 mo

    Working on quality control of antimicrobial susceptibility testing (AST) systems, focusing on method validation, standardization and compliance with EUCAST/CLSI guidelines.

  • Molecure (Full-time ยท 9 yrs 9 mos)
    • Senior Scientist / Translational Medicine
      Aug 2020 - Jun 2025 ยท 4 yrs 11 mos

      โœ… Designed and performed experiments leading to high-impact publications โœ… Scientific support for the clinical development of OATD-02 (ClinicalTrials.gov: NCT05759923) โœ… Co-leader of an undisclosed project on mRNA-targeting small-molecule therapeutics โœ… Prepared applications for animal studies to the local ethics committee; collaborated with external CROs and animal facilities โœ… Led the in vivo pharmacology group and mentored new team members in animal research and assay development โœ… Optimized animal models (syngeneic and xenograft tumor models, inflammatory disease models) for pharmacological testing โœ… Performed and analyzed PK/PD and efficacy experiments in various therapeutic areas โœ… Developed and refined enzymatic and cell-based assays, improving project outcomes โœ… Led pharmacodynamic and metabolomic studies on tumor microenvironment remodeling

    • Team Leader / Senior Scientist
      Jan 2019 - Jul 2020 ยท 1 yr 7 mos

      โœ… Co-led the OATD-02 arginase inhibitor project during its transition to the clinical stage โœ… Supported IND-enabling studies and liaised with the non-clinical safety team โœ… First author of the key publication validating OATD-02 as a dual arginase inhibitor with anticancer activity

    • Team Leader / Scientist II
      Aug 2017 - Dec 2018 ยท 1 yr 5 mos

      โœ… Biology co-lead of the arginase inhibitor project (OATD-02), responsible for experimental planning and execution โœ… Designed and conducted in vivo studies in syngeneic and xenograft tumor models โœ… Initiated and coordinated collaborations with academic groups to expand pharmacological profiling โœ… Co-authored several publications on arginase inhibition and immune modulation in cancer