Marek Pospíšil

GenAI Change Manager | OCM | Coach | People Leader

Basel, Basel, Switzerland

About

Senior leader with 25+ years of experience shaping and executing global digital and AI strategies within the pharmaceutical industry. Proven track record in building and leading global Centers of Excellence, translating complex strategic needs from scientific and clinical stakeholders into scalable, regulatory-ready solutions. Expert in driving the adoption of novel technologies, including leading a major GenAI upskilling initiative at Roche to enhance data-driven decision-making. Deep experience in Agile transformation, strategic portfolio management, and providing robust financial and operational oversight for multi-million dollar initiatives aimed at accelerating clinical value.

Experience

  • Roche (On-site)
    • GIG - Business Operations Lead (Dia Near Patient Care R&D)
      Sep 2025 - Present · 11 mos

      • Strategic Framework: Orchestrated a KPI-driven strategic framework for a 1,000+ member cross-functional organization (Molecular Science & HW/SW Engineering), balancing operational robustness with the agility required for near-patient care innovation. • AI Integration: Developed and deployed custom AI agents to automate methodological guidance and tactical operations, optimizing resource allocation and budget management for large-scale development projects.

    • Enterprise Agile coach
      Dec 2022 - Present · 3 yrs 8 mos

      • Provide enterprise-level Agile coaching, Program Management, and Organizational Change Management (OCM) to diverse business units, ensuring strategic initiatives align with corporate goals. • Assigned to various teams in Roche as an internal consultant.

    • GIG - EverydayAI Community and Engagement Lead (Corporate strategy)
      Jan 2025 - Dec 2025 · 1 yr

      • Architected and scaled a global AI enablement program, establishing the strategic framework, coaching, and resources to empower a network of over 2,500 AI Champions / 100,000 employees. Key Achievement: Orchestrated a scaled coaching model that successfully upskilled over 150 Lead Champions, creating a pivotal network for driving AI literacy and application, directly supporting Roche's strategic digital health and AI objectives.

  • Novartis (Prague, Czechia · On-site)
    • Global Solution Delivery Director (Web, Social, Mobile Center of Excellence)
      Apr 2017 - Sep 2020 · 3 yrs 6 mos

      • Established and led a global Digital Center of Excellence, managing a department-sized team (3 senior managers, 30 project managers, 120 project team members) to deliver solutions for 140+ global affiliates. • Directed a complex portfolio of over 200 concurrent digital projects, providing strategic and financial oversight for a +$30MM P&L to ensure value creation. • Manage a global network of external agency partners, establishing robust governance to ensure high-quality execution and cost optimization. Key Achievement: Sponsor the successful transition from Waterfall to a Scaled Agile Framework (SAFe) in a highly regulated pharmaceutical environment, achieving a 30% reduction in costs and a 50% improvement in 'time to market' KPIs through the rollout of a modular CMS platform.

    • Global Program Manager (Mobile Solutions Center of Excellence)
      Oct 2015 - Mar 2017 · 1 yr 6 mos

      • Lead a global project management team, centralizing the delivery of all Novartis mobile applications to establish consistent standards of functional excellence. • Hold ultimate accountability for ensuring all mobile solutions adhere to strict healthcare regulatory standards, including GxP and SOX, embedding compliance into the core delivery process. Key Achievement: Strategically scale the team's capabilities beyond mobile to include web and social solutions, successfully expanding the Center of Excellence's scope and impact.

  • Director - Web portals & Mobile solutions at Trask
    Jun 2013 - Oct 2015 · 2 yrs 5 mos

    • Direct a digital delivery department of 60 specialists, including project managers, analysts, and developers, fostering a culture of continuous improvement. • Lead the pioneering Internet of Things (IoT) program for Skoda Auto, delivering award-winning solutions that significantly advanced the client's digital capabilities. Key Achievement: Transform the department into a scalable service-oriented business, achieving a 30% year-over-year sales increase while converting a legacy CMS into a modular platform supporting 70 markets.

  • Project Manager / Freelancer at Dark Side a.s.
    Sep 2012 - Jun 2013 · 10 mos

    • As an independent consultant, manage a complex program integrating eCommerce, loyalty, and digital automation solutions, accelerating the client's digital adoption at scale.

  • Head of Project Management at Centrum Holdings, a.s.
    Oct 2010 - Sep 2012 · 2 yrs

    • Established and led agile PMO department (4 scrum masters) • Introduced strategic portfolio management (~12 concurrent projects) • Acted as a crisis manager for underperforming projects