Marek Lanč

Manager Preclinical Development | Cross-Functional, Data-Driven R&D & Asset Evaluation | AOP Health | IJF Kata Judge

Vienna, Austria

About

I am a cross-functional, data-driven, and innovative scientist with a strong foundation in physical chemistry and system-level constraints, focused on analytical thinking, problem framing, and evidence-based decision-making across R&D. I specialize in integrating experimental data, statistical analysis, and in-silico methodologies to evaluate complex scientific and technical questions, and I am driven by continuous learning. I contribute to strategic discussions in drug and medical device development, including asset evaluation and due diligence, translating physical-chemical constraints and uncertainty into actionable insights. I am motivated by roles that emphasize analysis, synthesis, and strategic reasoning, and I value clear communication of complex science to diverse stakeholders.

Experience

  • Manager Preclinical Development at AOP Health
    Jan 2024 - Present · 2 yrs 6 mos

    Design, analysis, and management of preclinical studies, due diligence, data analytics, and in-silico methodologies: - Contribute to the evaluation and due diligence of new drug candidates in strategic R&D and business development initiatives, with a focus on rare diseases. Supporting operational excellence initiatives. - Manage and implement in-silico tools and AI technologies within the Preclinical (R&D) department to support decision-making and predictive modeling. - Conduct business and pipeline analysis of the rare disease landscape relevant to AOP Health, integrating financial and R&D portfolio assessments. - Serve as preclinical manager for the preclinical research collaborative project in HematoOncology, in partnership with academia. - Perform preclinical evaluations of medical devices, including risk assessments, material compatibility (E&L), and biocompatibility studies in compliance with MDR (EU 2017/745), ISO 10993, and ISO 14971 standards. - Execute data analysis and statistical evaluation of pharmacology, pharmacokinetics, and toxicology studies using R and Excel. - Prepare and review non-clinical documentation, including RFIs, regulatory packages, and internal reports.

  • Business Development Analyst at Purency
    Feb 2023 - Jun 2023 · 5 mos

    Developing and assessing new business opportunities in the area of microplastic analysis/machine learning and generally in the area of analytical chemistry data analysis. (finished because the company was liquidated)

  • Research and development at Hubertus Goller Gesellschaft m.b.H.
    Oct 2022 - Feb 2023 · 5 mos

    Successfully finished a time-limited project on the investigation, root causes analysis and improvement of the blood-contacting medical device & coatings. The testing plan to investigate the surface properties was prepared, external partners managed and results translated to suitable improvement steps. In addition, a sub-project on the automatization of production logistics was designed and a system in VBA (Excel) forms was programmed.

  • University of Chemistry and Technology, Prague (10 yrs)
    • Assistant professor
      Jan 2019 - Dec 2022 · 4 yrs

      As a member of the Laboratory of membrane separation processes team, I am focused on the development, preparation, and characterization of gas separation membranes. My tasks consist of the detailed literature survey, analysis of problem solutions, measurement of original data, development of new analytical instruments and procedures for data analysis. I focus on polymers of intrinsic microporosity, polyimides, ionic liquids and graphene oxide.

    • Researcher
      2013 - Dec 2018 · 6 yrs

      As a member of the Laboratory of membrane separation processes team, I focused on the development, preparation, and characterization of gas separation membranes. My tasks consisted of the detailed literature survey, analysis of problem solutions, measurement of original data, development of new analytical instruments and procedures for data analysis. In centre of my interest were polymers of intrinsic microporosity, polyimides, ionic liquids and graphene oxide.

  • CCORE Technology GmbH (3 yrs 11 mos)
    • Consultant
      May 2022 - Oct 2022 · 6 mos

      Technical consultation on the developed system for the purposes of investment rounds.

    • Head of Research and Testing
      2020 - Apr 2022 · 2 yrs 4 mos

      Research and development of medical devices, new concepts and approaches in the area of blood oxygenation/decarboxylation. My strengths are in the comprehensive analysis of scientific and clinical data; their transfer to new ideas and development inputs. Within the company, I am responsible for the design of the in-vitro and in-vivo testing, and for supervision of (bio)chemical-engineering topics. I am leading the conceptual research of new membrane structures and coatings with the aim of their sustainable fabrication, process stability, and blood compatibility.

    • Research And Development Engineer
      Dec 2018 - Dec 2019 · 1 yr 1 mo

      Research and development of medical devices, new concepts, and approaches in the area of blood oxygenation/decarboxylation. The conceptual research of new membrane structures with the aim of their sustainable fabrication, process stability, and blood compatibility. Performing in-vitro and in-vivo testing of the system, and evaluation/modelling of chemical-engineering tasks.