Lucas Breen

Striving to help protect research participants, one research study at a time.

Tewksbury, Massachusetts, United States

About

Experience

  • Lahey Hospital & Medical Center ()
    • IRB Manager
      May 2022 - Present · 4 yrs 3 mos

      Develops and implements new and revised policies & procedures in consultation with the Director of Research Administration and Institutional Official; Provides guidance involving the interpretation of regulations, Federal and international guidance, and institutional policies to the organization’s IRB members, researchers, staff, and administrators; Determines appropriate path of escalation for any non-compliance issues; Serves as the Primary contact for all Ceded Reviews; Serves as the central point of collaboration for all components of the HRPP including planning and implementation; Responds to any research participant complaints; Works with the Research Quality Assurance Program to ensure compliance with all applicable policies and regulations; Establishes criteria for AAHRPP Accreditation

    • IRB Supervisor
      Jun 2017 - May 2022 · 5 yrs

      Reviews protocols and documents to identify regulatory issues and institutional policy issues; Determines which submissions qualify for expedited review; Provides guidance and training to investigators and research staff concerning federal research regulations, institutional requirements and IRB policies and procedures; Gathers information and material in response to inquiries and responds to requests for information regarding IRB review; Helps to provide educational materials for the IRB Members; Develops and revises Research Administration and IRB SOPs; Develops and revises application forms for IRB submissions; Conducts Expedited reviews and Exempt determinations of submitted research protocols and amendments; Directs management of IRB office staff of 3 employees; Ensures regulatory compliance with HIPAA, OHRP, and FDA regulations; Provides research compliance training to IRB staff, Committee members, and research staff on OHRP and FDA regulations; Documents minutes for Full Board meetings

  • Associate Director, IRB at Boston University Medical Campus
    Jul 2011 - May 2016 · 4 yrs 11 mos

    Oversees assignment of reviewers, meeting with staff and Board Chairs prior to meetings to review the agenda; Provides social, behavioral and educational research (SBER) expertise to four separate Full Committee staff and Committee members; Provides supervisory oversight for the IRB review of Exempt and Expedited studies; Tracks the processing of Exempt and Expedited reviews and monitors review times to ensure that benchmarks are maintained; Ensures regulatory compliance with HIPAA and FERPA; Provides research compliance training to IRB staff and Committee members; Provides training to IRB staff, Committee members, and research staff on OHRP and FDA regulations; Develops internal SOPs for review and processing of studies; Manages all aspects of the IRB staff and office in the absence of the Director

  • Research Officer at Harvard Medical School
    Oct 2003 - Jun 2011 · 7 yrs 9 mos

    Conducted assessment of research activities to ensure that they are planned, reviewed, and conducted in compliance with Federal and State Regulations and University policies and procedures; Performed technical pre-review of research applications with regard to protocol design, risk assessment, evaluation of review type, grant application, consent procedures, and study procedures; Monitored the Code of Federal Regulations, FDA, OHRP, and over-arching federal agencies for changes that affect research policies and procedures; Conducted pre-review of all protocol submissions reviewing them for content, accuracy, and completeness; Provided support to Investigators and study staff regarding Federal regulations and guidelines for conducting research; Met with medical student and post-doctoral investigators to assist in their preparation for conducting individual research projects; Prepared meeting minutes for assigned protocols sent to monthly full review IRB meetings; Conducted trainings for medical and dental students as well as Post-Doctoral employees; Provided technical support to ORSP staff.

  • Northampton VA Medical Center (1 yr 9 mos)
    • IRB Administrator
      Jun 2002 - Oct 2003 · 1 yr 5 mos

      Conducted assessment of research activities to ensure they are planned, reviewed, and conducted in compliance with VA, State, and Federal regulations; Worked in conjunction with Research Coordinator to conduct inspections of SOPs and policies of operational functions to determine compliance with laws, regulations, and principles guiding research; Monitored the Code of Federal Regulations, ORO, FDA, OHRP and other federal agencies for changes that affect research policies and procedures; Developed and coordinated record keeping and reporting capabilities with the Research Service for compliance issues; Created policies for ensuring compliance.

    • Psychology Technician
      Feb 2002 - Oct 2003 · 1 yr 9 mos

      Compiled data and performed data entry, coding, and cleaning for analysis; Performed initial screening assessments and obtained psychiatric histories for patient recruitment into various research studies; Performed psychological testing in weekly assessments of patients participating in research studies; conducted weekly individual therapy sessions with participants; Presented informational training sessions for staff to facilitate referrals; Devised procedures for optimal participant recruitment and retention; Performed site preparation for new protocols.

  • Clinical Behavioral Therapist at SUNBRIDGE OF HOLYOKE
    Jun 2001 - Feb 2002 · 9 mos

    Primary contact for caseload of 17 residents providing case management; Prepared and presented monthly, quarterly, and annual assessments of residents; Conducted intake evaluations of incoming residents; Provided individual therapy sessions with primary caseload focusing on specific diagnoses and behavioral issues; Conducted group therapy sessions on anger management, depression, substance abuse, borderline personality disorder, and other diagnoses; Developed teaching materials for group therapy sessions; Assisted staff Psychiatrist with separate caseload of patients, providing outreach and support regarding behavioral issues and medication changes.