Linda Gammage, PhD, MA

Sr. Principal Scientist/Sr. Director Clinical Imaging & Pathology, Merck & Co.

Greater Philadelphia

About

Experience

  • Merck (Full-time · 18 yrs 6 mos)
    • Sr. Principal Imaging Scientist, Research Science
      2019 - Present · 7 yrs 6 mos

      Expertise in medical imaging within the pharmaceutical industry both as a biomarker and clinical trial endpoint across early and late-phase oncology and immunotherapy trials. Collaborate cross-functionally integrating imaging into study design, protocol development, and regulatory submissions. Provide expert training and consultation on imaging response criteria used in clinical trials, including: RECIST 1.1, iRECIST, irRECIST, irRC (Wolchok), Cheson (hematologic malignancies), Lugano Classification and RANO (neuro-oncology). Cross-Functional Leadership: Collaborated with clinical development, regulatory affairs, translational medicine, and iCRO partners to ensure scientific rigor and consistency in imaging data across global studies.

    • Principal Scientist/Clinical Imaging Scientist
      2010 - 2019 · 9 yrs

    • PET/CT Research Physiologist/Manager
      2008 - 2010 · 2 yrs

      Led and conducted advanced preclinical imaging studies using PET/CT, SPECT, and CT modalities to support drug discovery and translational research efforts.

  • Chief PET/CT Technologist at Adler Institute for Advanced Imaging (AIAI)
    2005 - 2008 · 3 yrs

  • Trauma CT at John Peter Smith Medical Center
    2001 - 2004 · 3 yrs

    Provided emergency CT coverage Level I Trauma Center

  • Lead CT Supervisor at Osteopathic Medical Center University of North Texas (UNTHSC)
    2000 - 2004 · 4 yrs

    Lead CT Supervisor, overseeing weekend operations and supervising technologists in a high-volume clinical and research imaging environment. Provided advanced CT imaging services and supported interdisciplinary medical teams across a wide range of specialized procedures and research initiatives, including supporting an NIH-funded stroke research project for time-critical administration of tissue plasminogen activator (TPA) in acute ischemic stroke patients. Collaborated with surgical teams and UNTHSC researchers to support cutting-edge robotic surgery initiatives through high-resolution CT imaging and procedural planning. Emergency Imaging for the Ft. Worth Zoo performing emergency CT scans for exotic animals in coordination with zoo veterinary teams, ensuring timely diagnosis and treatment of critical conditions. Assisted radiologists and interventional specialists with CT-guided biopsies, drainages, and other minimally invasive procedures. Managed weekend imaging operations, ensuring optimal staffing, equipment readiness, and adherence to safety protocols. Demonstrated strong leadership, adaptability, and interdisciplinary coordination in both clinical and research-driven environments.

  • Trauma CT at Regional Trauma Center
    1985 - 1996 · 11 yrs

    Member of Level I trauma team acquiring CTs on critically injured patients; assisted with interventional CT procedures