Langen, Hesse, Germany
Chargenfreigabe von Immunglobulinpräparaten / Batch release of immunoglobulins Bioassays
Establishment of in vitro assays based on human immune cells for the investigation of mechanisms leading to the development of anti-drug antibodies. With special focus on anti-factor VIII antibodies (inhibitors) in hemophilia A.
Investigation of the species diversity of Plasmodia in humans and apes from Africa.
Research in virology (Orthopoxviruses). Construction and establishment of bacteriophage-based expression libraries for the characterization of the humoral immune response following an orthopoxvirus infection. Identification of a novel detection molecule using phage display technology. Establishment of a peptide-based ELISA assay for Orthopoxvirus detection.
Characterization of a zoonotic cowpox virus strain and investigation of rabies vaccine infectivity.
Investigation of cellular mechanisms responsible for exosome release from primary murine B-cells.
Research in tissue engineering / immunology. Long-term co-cultivation of immune cells in a perfused 3D lymph node bioreactor. Characterization of cell interactions through chemokine and cytokine measurements.