Zaragoza, Aragon, Spain
Study of cardiac ageing (MODELAGE)
Topic of research: Genetic engineering of human embryonic stem cells (ESC) and induced pluripotent stem cells (iPSC) using ZNFs and TALENs-mediated homologous recombination for: - Identification, isolation and characterization of human ESC/iPSC-derived lineage-specific cell types. - Gene correction to rescue defective phenotypes in patient-derived iPSC - In situ seamless correction/insertion of mutations in human ESC/iPSC - Cell imaging Experience in: - Cell culture and directed differentiation of hESC/iPSC - Genome editing using ZFNs, TALEN and CRISPR-CAS9 in hESC/iPSC - Molcular biology
Topic of research: Isolation and characterization of equine mesenchymal stem cells Experience in: - Isolation, cell culture of mesenchymal stem cells and characterization.
Topic of research: Analysis of candidate genes to QTLs related to fat metabolism in cattle. Experience in: - Identification and characterization of candidate genes - Genotyping of polymorphisms and association studies with milk fat traits in dairy cattle.