London, England, United Kingdom
Positions: Post Doctoral Research Fellow with the Thalassinos Lab, UCL, 2023 - Chair of The London Biological Mass Spectrometry Discussion Group (LBMSDG), 2025- British Society for Proteome Research Non-Officer Board Member, 2024- BBSRC Funded PhD Biomolecular Mass Spectrometry, Leney Lab for Biomolecular Mass Spectrometry, University of Birmingham, September 2019 – 2023 Non-Technical: Senior lab member (Thalassinos Lab): Responsibilities include developing research questions, driving projects, supervising PhD students, lab organisation etc… BSPR M. J. Dunne Fellowship Award 2024 Scrivens Symposium 2024 ECR Presentation Prize BMSS Biomacromolecular SIG 2023 Poster Prize BMSS 2022 Barber Prize for best oral presentation BGRS 2022 Presentation Prize IBBI 2022 Poster Prize Technical: Developing novel proteomics techniques, Crosslinking MS, Native MS, Top-Down MS. Interested in cellular protein biology, protein structure and PTM regulation (cancer, neurodegenerative diseases).
Thalassinos Lab Leveraging mass spectrometry techniques for the characterisation of structural biology across protein systems. We aim to use a combination of proteomics, ion mobility and native MS to probe how proteins behave in disease states, as well as investigating the assembly dynamics of viruses during host cell invasion.
Leney Lab for Biomolecular Mass Spectrometry Technical: • Chemical, biochemical and computational approaches to understand the signalling mechanisms that underpin breast cancer. Our long-term objective is to provide therapeutic solutions that counteract this disease. • Developed an LC-FAIMS-MS/MS technique that leverages ion mobility against tandem mass spectrometry to improve peptide isoform sensitivity and identify PTM crosstalk (First author publication: Manuscript in review). • Implementing my LC-FAIMS-MS/MS technique with SILAC proteomics mass spectrometry experiments to analyse the effect of phosphorylation and ubiquitination PTM’s in the context of fibroblast growth factor signalling. • Native & Top-Down mass spectrometry analysis of bacterial Sec machinery and algae-phycobilisome. • Other techniques: Mammalian cell culture, protein synthesis and purification, Liquid Chromatography, SDS-PAGE & agarose gel electrophoresis, PCR, organic chemistry synthesis including SPPS. • Computational Skills: Proficient in R, Microsoft Excel (for high-throughput data analysis), Mass Spectrometry data analysis platforms including PD, MaxQuant, Xcalibur, UniDec, MSFragger and much more, graphic design: Inkscape and GIMP. Non-Technical: • Oral Presentation at BMSS 2021 & Poster Presentation at ASMS 2021. • Founding and senior lab member responsibilities: Lab organisation, scheduling leader, regular group meeting/ journal club chair, training students (including demonstrating chemistry teaching labs), presentation of data etc…
Data collation and analysis pertaining to member charity expenditure and impact. Analysed member charity investment funds to generate birds eye view of the sectors financial management that would be used to better inform member charities. Roles also involved policy design, management and communications. Authored blogs relating to topical issues within medical research charity’s: Antimicrobial resistance and artificial intelligence in healthcare. Designed infographics for presentations and annual meetings.
Ghost authored a book ‘Morality vs Reality’ with author F. Tareen (2018).
Whilst home from university during summer holidays: I performed administrative tasks as well as answering the phones and greeting patients. As a separate role whilst working at the surgery, I designed a website for the GP and senior partner’s private medical licence company.