Houston, Texas, United States
Highly motivated and skilled Chemical and Biomolecular Engineer (PhD.). My research specialization is in modeling, simulating, and optimizing pharmacokinetics and pharmacodynamics systems. My goal is to use my broad modeling and experimental skills in new challenges within the field of drug development. Expertise: Modeling, Data Analysis, Simulation, Programming, Statistics, Process engineering, Experimental validation, PK/PD analysis, Process control. Software: NONMEM, R, MATLAB
Review Editor on the Editorial Board of Antimicrobials, Resistance and Chemotherapy
Quantitate Pharmacology & Pharmacometrics
“PKPD Modeling, Optimization and Treatment Prognostics from Modified Plate Reader Measurements for Resistant Fungi “Advisor: Dr. Michael Nikolaou; Associate Advisor Dr. Kontoyiannis o Experiments: Susceptibility breakpoints & Synergy assay Affiliated Organization: MD Anderson Cancer Center
Graded assignments and tutored undergraduate and graduate students: ▪ CHEE 6331 - Mathematical Methods in Chemical Engineering ▪ CHEE 4367 - Chemical Reaction Engineering ▪ CHEE 3321 - Analytical Methods for Chemical Engineers ▪ CHEE 3334 - Statistical / Numerical Techniques for Chemical Engineers
▪ Developed a Method to Distinguish Between Dead and Alive Bacteria from Optical Density Measurements when Bacteria are Treated or Not with Antimicrobial Agents ▪ Reverse Engineered the Above Approach to Allow the Medical device to Self-Calibrate the Data Produced ▪ Developed the New State of the Art for the Simultaneous Simulation and Experimentation of Multiple Drugs with Different Half-Lives. ( High Impact in Combinational Therapy) ▪Optimized the Design and Operation of a Hydrogen Network for Transportation Fuel
Development of a QSP Model for DLBCL NHL disease and application towards Cell Therapies ▪ Develop a QSP model for Diffuse Large B-cell Lymphoma ▪ Integrate the disease QSP model (Aim 1) with a cellular kinetic model of cell therapies to characterize expansion and persistence of CAR-Ts ▪ Explore multiple infusion (if any) datasets in DLBCL patients