Frankfurt Rhine-Main Metropolitan Area
New: DATA Analysis My scientific focus is on Mass Spectrometry; peptide & protein MS in areas like biotech (Proteomics & quantitative protein profiling, isobaric labelling, biomarker) and pharmaceutical industry (Antibodies, protein production, peptides and small molecules, GMP). I have preferences in science driven development of new ways of working - leaving well established limitations behind. Experienced in building a state of art MS Lab from the scratch. In Sanofi I lead a modern MS Lab and create knowledge and data to support the development of future biopharmaceuticals. "impossible" has a short lifetime - creativity together with team spirit across different disciplines enables to overcome well established limits and dogmas. (E.g. Tandem Mass tag, which allows today multiplexing of up to16 samples in one single run while delivering a relative quantitation for thousands of peptides in the samples. Such an innovation has enabled new applications.)
Lab Head at Industrial Affairs MSAT Analytics Nitrosamine Quantitation of Nitrosamines in pharmaceutical products
Drug Development - MS Characterization of Biopharmaceuticals Peptide profiling, Intact Protein characterization, Protein digest, Antibody characterization, Glycan patten, Glycation Biopharmaceuticals, Peptides, Insulins Structure elucidation of unknown impurities GMP compliance with high resolving mass spectrometer LC-MS, LC-ESI, LC-MALDI, MALDI Tof, ESI-Q-Tof, MALDI TofTof, Thermo Orbitraps: XL, Velos, Elite, Fusion ETD, Fusion LUMOS ETD & UVPD Isomer and epimer stereoisomer structure analysis of peptides
Head of Mass Spectrometry Project work in proteomics teams for method development and analytics Development of multiplexed quantitative Mass spectrometry: Tandem Mass Tag Tandem Mass Tag applications Project lead for Peptide labelling with Sensitizer tag for enhanced MALDI response
MS Research Scientist - first isobaric TMT experiment Setup of a new high throughput Proteomics MS Lab MALDI-MS, Nano-HPLC-ESI-Q-Tof-MS and MS/MS, Nano-HPLC-ESI-Ion trap-MS and MS/MS Gel based and gel free Peptide and protein profiling Project work in proteomics teams for method development and analytics Development of isotope labelled tags for chemical labelling of peptides Development of multiplexed quantitative Mass spectrometry: Tandem Mass Tag Project work in software development