Jordyn Markle

PhD, Biological Chemistry

Germany

About

I am a biophysical chemist whose interests broadly lie in protein biochemistry with relevance to human health. I have several years of experience in protein expression and purification in addition to many biophysical techniques such as NMR spectroscopy, circular dichroism, isothermal titration calorimetry, differential scanning calorimetry, thioflavin T assays, and fluorescence spectroscopy and microscopy. I recently completed my PhD in Biological Chemistry from Gary J. Pielak’s laboratory at UNC Chapel Hill, where my project focused on understanding the effects of macromolecular crowding on protein stability using NMR spectroscopy. Prior to entering the doctoral program at UNC, I graduated Valedictorian of my class with a Bachelor of Science in Biochemistry and Molecular Biology from Gettysburg College. I was an undergraduate research assistant for 3 years in the Frey Lab where I researched the interaction of huntingtin protein and prion protein with the cell membrane.

Experience

  • Postdoctoral Researcher, Buchner Lab at Technical University of Munich
    Apr 2026 - Present · 3 mos

    Researching the biophysics of Hsp90

  • University of North Carolina at Chapel Hill (3 yrs 5 mos)
    • Graduate Research Assistant, Pielak Lab
      Nov 2022 - Dec 2025 · 3 yrs 2 mos

      Analyzed the effects of macromolecular crowding by proteins via residue-level NMR complemented with other biophysical techniques

    • Graduate Teaching Assistant, Chemistry 101 Lab
      Aug 2022 - May 2023 · 10 mos

      Taught proper technique and lab safety to approximately 90 undergraduate students, held office hours, and graded assignments.

  • Gettysburg College (3 yrs 1 mo)
    • Biochemistry & Molecular Biology Mentor
      Aug 2021 - May 2022 · 10 mos

      Mentored sophomore biochemistry & molecular biology majors in areas such as course selection and choosing a research lab

    • Lincoln Scholar Mentor
      Apr 2021 - May 2022 · 1 yr 2 mos

      Mentored first-year students interested in the STEM fields and provided support and guidance during their transition to college life

    • Peer Learning Associate for General Chemistry
      Jan 2020 - May 2022 · 2 yrs 5 mos

      Provided tutoring and homework assistance to students enrolled in general chemistry