Paris, Île-de-France, France
Research focusing on: - understanding cancer immunogenic cell death (ICD) and immunosurveillance, - investigating the positive interaction between cancer immunosurveillance and autoimmunity, - developing cancer immunotherapeutic strategies. Expertise in oncology, immunology and virology. Group leader in "Tumor immunology, immunotherapy & virotherapy".
Head of a research group on "Tumor immunology, immunotherapy & virotherapy" within the team "Metabolism, Cancer & Immunity" of Prof. Guido Kroemer Research interests: - Investigating the mechanisms responsible for the positive link between some autoimmune manifestations and cancer immunosurveillance, - Deciphering the role of pattern recognition receptors (PRRs) & cytokines in cancer ICD, - In silico modelling of ICD, - Develop innovative combination strategies for cancer immunotherapy, with a particular interest in oncolytic viruses, vaccines, and immune and metabolic modulators. UMRS 1138 - Centre de Recherche des Cordeliers / CRC INSERM, Sorbonne Université, Université de Paris Director: Prof. Jessica Zucman-Rossi (2019-today)
Head of a research group on "Tumor immunology, immunotherapy & virotherapy" within the team "Metabolism, Cancer & Immunity" of Prof. Guido Kroemer Research achievements: - Revealed the benefit of caloric restriction mimetics (CRMs) in improving cancer immunosurveillance, - Developed potent immunotherapeutic strategies combining CRMs with immunogenic chemotherapies and immune checkpoint inhibitors, - Improved the efficacy of oncolytic vaccine therapy with immunomodulatory chemotherapy. UMRS 1138 - Centre de Recherche des Cordeliers / CRC INSERM, Sorbonne Université, Université de Paris Director: Prof. Jessica Zucman-Rossi (2019-today); Prof. Pascal Ferré (2014-2018) Fellowships: - Seerave Foundation (2018-2020) - Program for Cancer research and personalized medicine / CARPEM (2014-2016; 2020)
Lecture on "DNA vaccines for cancer therapy" Master2 - ITB (Immunologie Translationnelle & Biothérapies) - Module "Nouvelles stratégies vaccinales"
Lecture and tutorial-based course on "Virotherapy" (gene therapy, immunotherapy, phage therapy, oncolytic virotherapy) Master1 "Molecular and Cellular Biology" - UE4V145 "Virology"
Master2 Immunologie - EU6 Lectures to Master students on: - "Autophagy modulation for efficient cancer chemo-immunotherapy" - "Oncolytic viruses"
Head of a research group on "Tumor immunology, immunotherapy & virotherapy" within the team "Metabolism, Cancer & Immunity" of Prof. Guido Kroemer INSERM U1138 Research achievements: - Revealing the benefit of caloric restriction mimetics (CRMs) in improving cancer immunosurveillance, - Developed potent immunotherapeutic strategies combining CRMs with immunogenic chemotherapies and immune checkpoint inhibitors, - Improved the efficacy of oncolytic vaccine therapy with immunomodulatory chemotherapy. Gustave Roussy Cancer Campus Director: Prof. Jean-Charles Soria (2020-2021); Prof. Alexander Eggermont (2010-2019) Fellowships: - Seerave Foundation (2018-2020) - Program for Cancer research and personalized medicine / CARPEM (2014-2016; 2020)
Lecture on the "Modalities of tumor cell death" to Master's students
Lecture on the "Role of the immune system in the efficacy of chemotherapy" to students, researchers & clinicians