Biberach an der Riß, Baden-Württemberg, Germany
Chemical biologist with >10 years research experience, now driving biologics drug development. Experienced in project managment and team leadership. Research experience in proteomics, protein chemistry and analytics, and cell signalling. Functional CMC lead in preclinical and clinical biologics development project teams in immunooncology and inflammation indications.
• Functional CMC lead in preclinical and clinical biologics development project teams in immunooncology and inflammation indications. Management of 3M € / year project expenditure. • Experience with modern biologics formats (bispecific mAbs, t-cell engagers, fusion proteins). • Matrix manager of 6-10 technical staff in parallel teams. Comfortable with leadership in German. • Initiated two independent scientific projects. Hired and supervised a postdoctoral fellow.
With Dorothea Fiedler • Developed pyrophosphoproteomics to identify first endogenous protein pyrophosphorylation sites in human cells, and synthesised model proteins and peptides to characterize this post-translational modification. • Broad project design and project management experience across the fields of chemical biology, molecular biology and biochemistry.
With Chris Easton • Characterized the biosynthesis of biomarker peptide hormones in cancer cell lines using HPLC-fluorescence, and identified compounds in vitro that disrupted or stimulated hormone production.