Biel, Berne, Switzerland
• Scientist focusing on research and development of novel chemicals and solutions in the sector of materials and construction. • Solid expertise gained during more than 10 years in the field of organic, analytical, and polymer chemistry, formulation and admixture development, cement chemistry and concrete technology. • Experience in developing and deploying on sites new technologies and tailored solution for various customers (concrete, precast, cement production) worldwide. • Strong team player, target and result oriented with a focus on sharing, learning and networking. Solid interpersonal skills, analytical, logical and able to make decisions to drive projects to success ahead of schedule.
Leading Corporate Research Projects: development of new admixture chemical building blocks & technologies. Technology transfer of new leads to Corporate Development, Target Market and to local operations. Corporate technical support for admixture formulation, organic chemicals and building blocks. Implementation and worldwide training of SIKA new Global Digitalization tool for big data and Artificial Intelligence.
Definition, management and execution of the Admixtures R&D project portfolio to support company priorities on CO2 reduction, sustainability development and urban solutions. Management of interaction and strategic collaborations with key chemical raw materials suppliers. Development and implemention of IP-protected proprietory chemicals and technologies (5 patents). Coordination of the Admixtures Global Technical Network for sourcing strategy and technology dissemination across 13 countries. Technical leadership for the start-up of 5 new production sites worldwide. Co-Owner of the CEMEX Admixtures Academy for Training & Mentoring of junior talents.
Admixture and New Products Researcher at the R&D Center of Cemex in Switzerland. Deputy of the Admixture Technology Development Manager Developing and implementing on-site, new admixtures solutions and technologies Developing and deploying worldwide, new concrete products Training and supporting local champions for the implementation of new products Supporting the commercialization of new products
Temporary Research Fellow on “Application of continuous flow chemistry in medicinal research” • Implementing and evaluating the use of continuous flow chemistry on two important reactions: - 1,3-dipolar cycloaddition of azomethinylides with dipolarophiles. - Pfitzinger reaction. Key Achievements: - Developed expertise in continuous flow chemistry and VapourTecTM equipment. - Successfully set up both reactions as a continuous flow process. - Synthesis of biologically active compounds. - 1 publication in preparation.
Post-Doctoral Fellow on “Identification of substrate binding site tyrosine kinase inhibitors via a substrate activity screening” • Implementing a kinetic enzymatic assay for the monitoring of substrate phosphorylation. • Collaborating with biologists and kinase experts. • Mapping of protein-protein interactions between a kinase and its substrate. • Enhancing peptidic and semi-peptidic substrate binding efficiency. • Generating substrate-targeted inhibitors. • Delivering project ahead of schedule. Key Achievements: - Developed expertise in SPPS, in-vitro biochemical assay and enzymology. - Over 300 compounds synthesized, purified and evaluated. - Improvement of substrate efficiency by more than a factor 50. - Identification of a single-digit micromolar substrate-targeted inhibitor. - 2 publications, 1 poster at an international conference, 4 posters at internal conferences, project presented to 2 boards of leading scientists.
Chemist on “Combinatorial organic synthesis” (Internship) • Responsible of synthesizing a library of 4,6-diaminopyridines by solid phase synthesis. • Optimizing reaction conditions. Key Achievements: - Developed expertise in solid phase combinatorial chemistry. - Over 10000 compounds synthesized: 1 lead compound identified. - Worked independently and successfully achieved 3 projects.
Scientist on “In-Silico methods for drug discovery” • Responsible of registering new and old compounds in the Novartis database. • Classifying products according to their chemical and physical properties. • Literature search Key Achievements: - Over 3000 compounds registered and classified. - Trained and coached other trainees.