Basel, Basel, Switzerland
Research on the role of different interneuron subtypes in learning and memory in health and disease in Prof. Josef Bischofberger's lab. Supervision of student projects (e.g. Lodge et al., Cell Rep 2021).
Projects on the role of GABAA receptors containing the α5 subunit (α5-GABAARs) in the hippocampus in Prof. Josef Bischofberger's lab. We demonstrated that inhibitory synapses on the dendrites of CA1 pyramidal neurons contain these receptors which are activated by specific interneuron subtypes. α5-GABAARs convey unique voltage-dependent properties to dendritic GABA synapses that allow them to regulate NMDAR activation and synaptic plasticity (Schulz et al., Nat Comm 2018; Schulz et al., J Neurosci 2019).
Project on GABAB receptor-mediated inhibition of dendritic spikes and dendritic integration in cortical layer 5 pyramidal neurons in Prof. Matthew Larkum's lab (Palmer, Schulz et al., Science 2012; Schulz et al., Front Cell Neurosci 2021).
Brief project to support the characterization of synaptic short-term plasticity at convergent inhibitory synapses to the substantia nigra pars reticulata, one of the output nuclei of the basal ganglia (Connelly et al., J Neurosci 2010).