Mumbai, Maharashtra, India
"Experienced Senior Research Investigator with expertise in medicinal chemistry and multi-step organic synthesis, supported by 26 publications in high-impact journals. Strong background in organic chemistry, medicinal chemistry, drug discovery, and structure elucidation". Proficient in solving complex synthetic challenges through the design and development of efficient multi-step synthetic routes. Demonstrated expertise in structure-based design and synthesis of small molecule kinase inhibitors and heterocyclic scaffolds, with deep experience in multi-parameter optimization (MPO) strategies. Successfully designed and developed novel type-II and allosteric kinase inhibitors, generating a library of over 600 small molecules. Extensive experience in hit-to-lead optimization in both academic and industrial settings. Proven ability to lead and participate in cross-functional meetings to drive collaborative drug discovery efforts forward.
Worked at QureTech Bio AB (2020–2023), collaborating with senior scientists and biologists on the design and synthesis of ring-fused tricyclic 2-pyridone derivatives targeting antimicrobial resistance. Developed a photocatalyst-free, visible-light-mediated, regio- and diastereoselective [2+2] cycloaddition of thiazolo-2-pyridones with styrenes.
Worked at Umea University, Sweden in Prof. Fredrik Almqvist Research group for 2 years. The postdoctoral research was focused on the Design and synthesis of ring-fused Tricyclic 2-pyridone target molecules for neurodegenerative drug discovery. Where I have been awarded the prestigious Kämpes Foundation Fellowship in 2018 for outstanding postdoctoral research contributions.