South Yarra, Victoria, Australia
As a dedicated Master's student at Monash University, specializing in Biomedical and Health Science, my fervour lies in pioneering advancements in global health through cutting-edge biomedical research. My focus is specifically drawn to the realm of inflammation and immunity, where I am deeply intrigued by the intricate mechanisms governing cell signalling and pathway regulation. During my tenure in the Master's program, I had the privilege of participating in a rigorous 9-month research project at the Hudson Institute of Medical Research, spanning from 2023 to 2024. Within this immersive experience, my attention was centred on unravelling the complexities surrounding the expression and regulation of Interleukin 1 family cytokine receptors, both in states of health and inflammation. This journey has equipped me with a diverse skill set encompassing various laboratory techniques and analytical methodologies, nurturing a profound fascination for immunology. As I near the culmination of my Master's degree, I am actively seeking avenues to further contribute to the biomedical landscape. Whether it entails pursuing a doctoral degree or securing a role as a Research Assistant, I am poised to channel my passion and expertise towards steering impactful research endeavours.
Sessional Academic, Obstetrics and Gynaecology at Monash Health, School of Clinical Sciences at Monash Health, Faculty of Medicine Nursing and Health Sciences • Delivered teaching sessions and presented theoretical content to third-year undergraduate students. • Demonstrated laboratory experiments and pre-clinical techniques. • Assessed and marked student reports, providing constructive feedback to support learning outcomes.
The broad objective is to explore the unknown mechanisms by which BPD/PH causes long-term morbidity and mortality later in life. Animal will be subjected to an established BPD/PH model (Nold et al., 2013) and thereafter exposed an asthma model. In addition, my team has shown that anakinra (IL-1Ra), a safe and effective drug, which has been used in clinical medicine for more than 20 years, dramatically improves the outcome of BPD. Here in my project will aim to assess further if IL-1Ra in comparison to anti-inflammatory strategies (dexamethasone) also improves later life lung health, such as in Asthma. Supported by Monash Graduate Scholarship (MGS) and Monash International Tuition Scholarship (MITS).
• Expanding the master’s research project and learning some additional techniques, such as Plate-based binding assays • Identify the molecules against a selection of receptors of interest; Demonstrate binding of targets to its potential receptors • Perform data analysis that contributes to the potential publication of the lab
The Nold group aim to better understand how inflammation drives newborn and early-life diseases of the premature heart and lung such as bronchopulmonary dysplasia (BPD), pulmonary hypertension associated with BPD (BPD-PH) and necrotising enterocolitis (NEC) affecting the immature gut, which will assist in the design of new diagnostic techniques and underpin the development of innovative anti-inflammatory drugs. During my Master’s program, I engaged in a comprehensive 9-month research project at the Hudson Institute of Medical Research from 2023 to 2024. This experience focused on the expression and regulation of Interleukin 1 family cytokine receptors in both healthy and inflammatory states. Throughout the project, I developed and applied various laboratory techniques and analytical methodologies, deepening my passion for immunology through hands-on research and analysis. • Investigating glomerulonephritis and exacerbated kidney disease in a murine IL-1 family cytokine knock-out model • Interleukin 1 family cytokine receptor expression and regulation in health and disease and intracellular function •Completed a thesis titled "Investigating the role of IL-1 family cytokine receptors in health and disease"
Participate in the 10-week research project at the Cathaypath Institute of Science with Prof Arthur Salomon from Brown University. The course is about the investigation of the molecular basis of cancer, environmental toxicants, and Chinese traditional medicine. • After the study, I wrote a proposal with topics KO MAT2A to further inhibit hypomorphic PRMT5 in MATP-deficient TNBC cells for metastasis suppression in vivo and in vitro. • During this study experience, I learned the basic logic of how to design an experiment, and how to turn the knowledge that we learned in the textbook into a real case.
Experienced in working with animals. I am dedicated to creating a stress-free and positive experience for the animals I work with, ensuring their happiness and well-being.