Munich, Bavaria, Germany
Working on antisense oligonucleotide (ASO) development as therapeutics
Investigated the effects of aggregating proteins in cell lines and primary neurons. This work resulted in a first-author scientific publication. Contributed to two successful collaboration projects investigating the structural and cellular effects of a-synuclein and tau aggregation, hallmarks of Parkinson's and Alzheimer's disease pathology.
Thesis title: Artificial amyloid-like aggregating proteins cause cytotoxicity in vitro and in vivo. Supervisors: Prof. Rüdiger Klein and Dr. Irina Dudanova Studied how protein aggregation affects neuronal viability, both in vitro and in mouse models. My results provided further knowledge on neurodegeneration mechanisms and set the grounds for the preparation of two scientific publications.
Analyzed a zebrafish line to assess its potential use for development and regeneration studies, thereby contributing to my supervisor´s PhD work. Supervisors: Prof. Michael Brand and Dr. Peggy Jungke
Expression analysis and functional characterization in zebrafish CreERT2-driver lines in various organs
Expression analysis and functional characterization in zebrafish CreERT2-driver lines in various organs
Analysis of the SDF-1 promoter activity in human mesenchymal stem cells (MSCs) . Supervisors: Prof. Martin Bornhaeuser and Dr. Regina Duryagina