Holly Uber

Product & Innovation Leader | Digital Health & AI | Human‑Centered & Data‑Driven Programs | Governance, Risk & Responsible AI | Public Speaker

San Francisco Bay Area

About

As a product and innovation leader with over a decade of experience in edtech and healthcare technology, I turn complex, high‑accountability problems into breakthrough solutions by bringing together technology, science, and human potential. Most of my work lives in highly regulated, public‑interest environments where innovation has to earn trust through equity, safety, and measurable outcomes. ​ My leadership journey spans education, digital health, and emerging technology, and I have consistently pushed what is possible in service of the people using the systems we build. I have not only designed new products and programs but also built and run the operating models, teams, and partnerships that make them work at scale. ✅ Developed award‑winning AR/VR/XR learning experiences that reached over 1 million students, including the programs, training, and support needed for successful classroom adoption. ​ ✅ Led strategy and delivery for Roche’s first commercial SaMD for remote vision patient monitoring, partnering with clinical, regulatory, quality, and operations teams to navigate FDA and quality requirements and stand up ongoing service delivery. ✅ Catalyzed innovation in Personalized Healthcare by leading the Bridge Forum, engaging 80+ participants in bi‑monthly knowledge‑sharing, governance, and operating‑model conversations across functions. ✅ Invested in and supported startups as a strategic VC and angel due‑diligence lead focused on health and education, with a lens on scalable business models, operations, and impact. ​ Core strengths: 🔹Systems‑level thinking in complex, regulated environments 🔹Technology and data‑driven innovation grounded in evidence, performance, and outcomes 🔹 Inclusive and human‑centered design that centers equity and access 🔹 Strategic partnership and ecosystem development across sectors 🔹 Translating policy, risk, and regulatory constraints into clear product, operations, and service priorities ​ I am especially interested in how AI, data, and emerging technologies can be deployed responsibly at scale, earning trust through transparency, governance, and human‑centered design. I care about community‑driven innovation and expanding what is possible in healthcare, education, and public services. Let’s connect if you are focused on transforming services or building digital and data infrastructure and operating models that are genuinely accountable to the people they serve.

Experience

  • Funding Breakthrough Lab – Leadership Team at Funding Breakthrough Lab
    Jun 2025 - Present · 1 yr 1 mo

    Serve on the leadership team for a nonprofit pre‑accelerator that supports early‑stage founders with fundraising education, investor access, and peer community. Co‑design and facilitate cohort sessions that help founders clarify funding strategies, test go‑to‑market assumptions, and connect with investors and operators.

  • How Women Lead Silicon Valley Executive Board at How Women Lead
    Nov 2024 - Present · 1 yr 8 mos

    * Champion How Women Lead’s mission by shaping strategic vision and convening high‑impact gatherings that elevate diverse women leaders. * Design and facilitate interactive sessions on AI branding, storytelling, and user journey optimization that create psychologically safe spaces for experimentation, peer coaching, and honest reflection.

  • Programming Director at Large - San Francisco at Healthcare Businesswomen’s Association
    Mar 2022 - Present · 4 yrs 4 mos

    * Design programs that convene diverse healthcare leaders in interactive forums for learning and collaboration, using lightweight playbooks that scale member engagement revenue targets. * Honored with the Marie Curie Award 2025, HBA LEAD Award 2024, and Spark Award 2023.

  • Genentech (4 yrs 5 mos)
    • Director of Product
      Mar 2022 - Aug 2024 · 2 yrs 6 mos

      Successfully developed and launched one of Roche’s first Software as a Medical Device (SaMD), achieving FDA registration to meet Roche corporate goals. Led product development for an app deployed in 3 clinical trials, leveraging data analytics to optimize adherence for 400+ patients across multiple clinical applications to meet protocol and data requirements. * Directed end-to-end product roadmap, strategy, and technical development for myVisionTrack, an at-home vision monitoring app and HCP monitoring portal solution for patients with retinal diseases. * Managed multiple strategic partnerships, notably with the Legal Manufacturer, overseeing contracting, compliance with Quality Management Systems, and risk mitigation across global operations. * Built governance processes to support auditability, documentation, and long-term compliance with QMS. * Fostered alignment with cross-functional stakeholders, including therapeutic area, regulatory, legal, quality teams, cybersecurity, commercial and medical affairs to ensure smooth product development and launch. * Advised executive leadership on regulatory risk, launch readiness, and post-market obligations Chaired the Digital Device Working Group, unifying device development management across global operations. * Establishing or refining processes/standards for digital health products. * Drove innovation in the Personalized Healthcare organization by leading the Bridge Forum, engaging 80-120 participants in bi-monthly knowledge sharing initiatives and built a culture of learning. * Implemented inclusive design processes, partnering with advocacy boards to align products with diverse patient needs across the patient journey. * Nominated for the 2023 Genentech Changemaker award for digital health innovation contributions. * Pioneered the design of immersive VR therapeutic for ASD, collaborating with neuroscience team on study design and endpoints. Developed content strategy to foster behavior change.

    • Principal Product Manager
      Apr 2020 - Mar 2022 · 2 yrs

      Personalized Healthcare Center of Excellence (PHC) - Digital Health

  • zSpace, Inc. (5 yrs 7 mos)
    • Director, Education Product Management
      Nov 2018 - Apr 2020 · 1 yr 6 mos

      Executed product strategy and development for a world-class AR/VR platform, delivering innovative digital solutions for STEM education and training including healthcare. * Produced 30+ award-winning AR/VR education simulations, enhancing product offerings and driving significant sales renewals. * Developed enablement materials to train over 50 internal staff across sales, customer success, and support teams, fostering a culture of collaboration. * Managed 4 external global development teams while collaborating with 3 internal teams to scale the business. * Evaluated third-party products for strategic partnerships, successfully acquiring 5 new partners that expanded market reach and enhanced product capabilities. zSpace delivers the ultimate learning experience to inspire curiosity and accelerate understanding. Our product, zSpace®, combines elements of VR and AR, on an all-in-one computer, to create lifelike experiences that are immersive and interactive. Among its numerous awards and accolades, zSpace was named “Cool Vendor” by Gartner, Inc., “Best in Show at ISTE” by Tech & Learning Magazine for three consecutive years and was named to Fast Company’s prestigious annual list of The World’s Most Innovative Companies for 2019. zSpace is a privately held, venture backed company located in Sunnyvale, California, and has been granted more than 50+ patents for its innovative technologies. For more information, visit www.zspace.com.

    • Senior Customer Success Manager and Product Strategy
      Oct 2017 - Oct 2018 · 1 yr 1 mo

    • Professional Development Manager & Educational Specialist
      Oct 2014 - Sep 2017 · 3 yrs