Henri Motte

Site QP - Head of Quality Operations & External Affairs at Thermofisher Large Molecules ( Viral Vector Services)

Héron, Walloon Region, Belgium

About

PERSONAL PROFILE Industrial pharmacist by training, I am an experienced leader in the GMP pharmaceutical environment with significant accomplishments in Pharmaceutical Development and Manufacturing. Looking for a leadership position to share my experience, collaborate with various stakeholders, lead and coach teams to reach objectives. I am both a team player and a dynamic leader, passionate and enthusiast. What I can offer with my swiss knife profile? SKILLS Team management and coaching • Animate a team and make the work pleasant, build trust truly • Take responsibility for my team, be a leader, coach and advisor • Remove rocks on the road, solution oriented • Work as a team player, communicate openly and sustainably achieve team objectives • Assess and develop the team with an appropriate training plan and be accountable for the team efficiency • Collaborate with a collective and emotional intelligence • Manage OPEX and CAPEX budget of the department Quality and HSE • Perform the QA review of deviation notification and lead investigation • Perform pharmaceutical drug product/finished good release as QP • Implement and manage QMS with regards to HSE, Quality, Cost and Delivery, including Industry 4.0 concept (Deviation, Investigation, CAPA plan) • Provide expertise related to business processes from raw material to drug product (Eudralex, ISO - ICH Q8, ICH Q9, ICH Q10) • Familiar with internal and regulatory audits related to GMP purpose • Collaborate transversally to ensure all quality requirements are in place • Continuous improvement of business processes Project Management / PMO • Lead project and portfolio from ideation to closure with an effective tracking of gates deliverables, timelines, budget and health (KPI's) • Plan and execute project, manage people and capacity, forecast resource • Coordinate project teams and stakeholders through steerco meetings and governance body • Collaborate with finance, purchasing, suppliers and external stakeholders (Universities, equipment suppliers, consultancy agencies, institutional organisation eg. Walloon Region) • Lead monthly project review with the management accordingly to governance • Generate new ideas and proposals for global implementation, identify process gaps/areas for process improvement, develop and implement solutions for operational methodology and optimization of processes • Hold the change management and support PM community to reach the objectives with support from the management

Experience

  • Thermo Fisher Scientific ()
    • Site QP / Head of Quality Operations and External Affairs
      Feb 2025 - Present · 1 yr 6 mos

      Manage, lead and reorganise the QA operational and External Affairs teams for further organisational dimension. Shape and lean Quality processes.

    • Site QP / Head of Product Quality & External Affairs
      Jul 2024 - Jan 2025 · 7 mos

      Lead a team of QPL's and act as a Quality Product Lead, exchanging with customers about Quality, QC and Regulatory matters (Europe, US and Japan) for IND. Act as Qualified Person, interact transversaly with internal stakeholders (USP/ DSP/ F&F) to assess productions risks , deviations and OOS. Interact closely with QA Operational for batch review and release of clinical batches.

    • Lead QP
      Nov 2023 - Jul 2024 · 9 mos

  • Program manager at Nalys
    Jan 2023 - Nov 2023 · 11 mos

  • UCB (7 yrs 9 mos)
    • Transversal Portfolio Manager - Associate Director
      Feb 2020 - Sep 2022 · 2 yrs 8 mos

      - Implementation of a PMO Transversal Governance through the Pharmaceutical Development Department - Improve the management of projects, training and coaching of project managers and follow-up of capacity management and budget (eg. gate/milestones, resources, budget & risks) to ensure an effective prioritization and decision-making within departments - Responsible person for Change Management through the teams and implementation of new processes and use of PM tool (Planisware)

    • Head of Manufacturing and Process Technology - Associate Director
      Aug 2018 - Feb 2020 · 1 yr 7 mos

      - Develop strategy of investment and resource allocation to reinternalize projects developed externally - Grow and engage manufacturing team to deliver faster and safer CTM - Lead the strategic transformation of the conventional processes into the Industry 4.0 concept

    • Head of Pilot Plant - Associate Director
      Jan 2015 - Aug 2018 · 3 yrs 8 mos

      Accountable for GxP Compliance, Equipment and Premises. I am currently the accountable person for the complete revamping of the pilot plant and the implementation of a fir-for-purpose ERP to drive our business processes through a lean and agile IT solution and efficient SOPs. Taking care of my team, we grow all together...

  • Clinical trial manufacturing - Pilot plant manager at UCB
    Aug 2009 - Dec 2013 · 4 yrs 5 mos

    - Operational management of the pilot plant & warehouse in accordance with GMP compliance, in order to pass successfully audits and deliver GMP Clinical trials. - Responsible person for the implementation of Process Analytical Technology (PAT) on equipment and QbD in formulation/process development (e.g. NIR, FBRM, Raman and DoE) - Set up and control of department budget (DOA) - Set up of business cases for continuous improvement or for life cycle management of mature products - Set up of a technology platform in collaboration with universities and pharma companies - Continuous Business improvement within the department : simplification of SOPs regulating the pilot plant in order to establish efficient workflows - Accountable for purchasing, set up and qualification of new equipment for pharmaceutical development - Project management for the refurbishment of the pilot plant - Project leader for DP formulation optimization - HSE responsible person for the pilot plant

  • Pharmaceutical Process Engineer at UCB
    Dec 2007 - Jun 2009 · 1 yr 7 mos

    - DP project leader : set up of the new manufacturing line of equipment (dry granulation), coordination between different services to set-up, qualify equipment and launch the first clinical trials. - Optimization of Zyrtec-D process : improvement of the formulation - Atarax project leader : to drive and lead the change control regarding the new drying process of hydroxyzine and control impact on DP.