David Henke, M.P.H.

Senior Biostatistician @ Baylor College of Medicine | MPH, Biostatistics

Salt Lake City, Utah, United States

About

I am a Senior Biostatistician at Baylor College of Medicine with over a decade of experience in data analysis and biostatistics. I have a Master of Public Health degree in Biostatistics from UNC Chapel Hill and multiple publications in prestigious journals such as Nature Communications and European Respiratory Journal. My mission is to use my skills and expertise in genomics and population genetics to create health outcomes through actionable biomedical solutions. I am passionate about exploring the influence of viral genomes on clinical outcomes and characterizing the respiratory syncytial virus genome. I have successfully developed genomic investigative tools for both academic and clinical applications, such as a clinical diagnostic analytical tool and an interactive web-based application. I also lead and manage projects that involve collaboration between different disciplines, such as single cell, copy number analysis, genetic signature associations, cancer survival, and SNP association.

Experience

  • Baylor College of Medicine ()
    • Senior Biostatistician
      Nov 2017 - Present · 8 yrs 9 mos

      * Develop pipeline for viral genomes influence on clinical outcome analysis * Characterization of the respiratory syncytial virus’ genome though private and public data * Statistical analysis methods: bootstrapping, phylogeny, ensemble learning, and mixed model regression

    • Statistician
      Jul 2016 - Nov 2017 · 1 yr 5 mos

      * Project management and statistical analysis for projects: single cell, copy number analysis, genetic signature associations, cancer survival, and SNP association * Clinical diagnostic analytical tool development * Analyses for clinical, RNA-seq, DNA-seq, and microbiome data * Data engineering projects: xenograft alignment and interactive web-based application * Genomic computing using HPC cluster * Statistical analytical methods: regression, power calculations, survival, and odds ratio

    • Bioinformatician
      Mar 2015 - Jun 2016 · 1 yr 4 mos

      * Statistical analyses: microbiome clustering analysis for nonlinear regression clinical outcome modeling and estimation of fold change expression differences in in vitro cell models * Collaborated with investigators to successfully complete grant and paper submissions * Developed tailored, interactive, web applications to aid collaborative data analysis * Statistical analytical methods: k-medoids clustering, silhouette clustering, and nonlinear regression

  • Statistical Consultant at The Renovion Group, Inc.
    Feb 2014 - Present · 12 yrs 6 mos

    https://www.renovion.com/

  • Statistical Consultant at UNC Department of Surgery
    Jan 2014 - May 2014 · 5 mos

  • Master's Student at University of North Carolina at Chapel Hill
    Aug 2012 - May 2014 · 1 yr 10 mos

    Masters paper under the direction of Dr. John Preisser Jr: “Logistic Regression Modeling: Compensating for an Incomplete Covariate via Use of Weights”

  • Genetics Lab Researcher at NIEHS
    Oct 2009 - Jul 2012 · 2 yrs 10 mos

    * Programmed and maintained large automated pipetting machines, acted as liaison between labs, and trained two technicians * Received annual Distinguished Achievement Award: 2011, 2012 for implementing a cost effective and environmentally sound technique for genotyping and sequencing; contributing to achieve a positive annual budget