Bentonville, Arkansas, United States
Molecular biologist with 20+ years of academic and industry experience in genetic and protein engineering, diagnostics assay development, and biotechnology innovation. Skilled in gene cloning, protein expression, CRISPR-based editing, and assay validation, with proven success in leading research teams and advancing projects from concept to application. Experienced in protein purification, bioprocess development, and cancer tissue culture, with a strong track record of mentoring researchers, driving data-driven solutions, and delivering impactful results in molecular biology and diagnostics
As Director of R&D at NowDiagnostics, I lead the development of innovative over-the-counter and point-of-care diagnostic products that make testing faster, simpler, and more accessible. I oversee our scientific strategy and product pipeline while guiding a talented team of scientists and research associates, fostering a culture built on collaboration, rigor, and continuous learning. I’m responsible for driving product development from early concept through clinical studies and regulatory milestones, including direct communication with the FDA. I also oversee preparation of protocols, reports, SOPs, and other regulatory documentation, and support the company’s intellectual property and patent strategy.
• Cloning of Gmd, WcaG, LAC12, FucT2, and FuTA genes in S. cerevisiae using CRISPR method to Synthesis Human Milk Oligosaccharides (HMOs). • Working on a novel high-profile water treatment project to eliminate water toxicity caused by super toxin microcystin (MC-LR) produced by cyanobacteria using biodegradation methods. • Cloning, expression, and purification of MC-LR degradation enzymes. • Developing a natural product anti-cancer ¬¬¬agent (fucoidan) for breast cancer. • Cloning, expression, and purification green fluorescent protein (GFP) fused with metal binding peptide for biomimetic nanoparticle synthesis for catalytic application. • Design, expression, and purification of several version of COVID-19 spike proteins to develop an immune base assay for diagnostic purpose collaborated with a local company in Arkansas. • Developing next generation contact lens case for covid-19 diagnostic applications. • Design validation chromatography experiment for syntactic covalent organic frameworks (COFs) as a cutting-edge bio-separation ion-exchange chromatography tool for pharmaceutical applications. • Mentoring undergraduate and graduate students, and postdoctoral researcher to express and isolate recombinant protein using microbial host.
• Cloning, expression, and purification of Basic Fibroblast Growth Factor Fused to two Collagen Binding Domains expressed in E. coli BL21 using Flask and fed-Batch • Mentored undergraduate and graduate students to express and isolate recombinant protein using microbial host. • Teaching assistant in the Department of Chemistry and Biochemistry.
• Elucidated mode of action of biologically active natural products and small molecules with nano molar inhibition against cancer cells in vitro. • Examined cytotoxicity effects of synthetic small molecules against cancer cells in vitro. • Investigated mechanism of cells death mode caused by bioactive natural products and small molecules.
• Provide technical support to customers, identify new product applications, and provide feedbacks on further product improvements. • Responding to customer inquiries and offering technical solutions, as well as building and maintaining strong customer relationships. • Leading Covid-19 diagnostic test efforts cooperating with the health ministry in Iraq. • Multiple projects include the lab installations in medical, science, and engineering schools in Iraq. • Supervised effective marketing and leadership initiatives across country to spread awareness about the organization services.
Taught courses in: Natural Products, Genetic Engineering Techniques, and Biochemistry.
Developed a natural product L-asparaginase as anti-cancer agent. L-asparaginase extracted and purified from pathogenic Escherichia coli which was isolated from urinary tract infection patients.
• Taught Genetic Lab.
Extraction of oxytocin like effects from Iraqi date palm.