Germany
Alliance management of the Bayer - Broad Cardiovascular collaboration
Study the role of pericytes in angiogenesis in vivo in the lab of Prof. Dr. Ralf Adams • Characterize novel transgenic mouse lines to genetically modify pericytes in vivo • Loss of function studies to specifically address the involvement of pericytes in the development of the mouse retinal vasculature • Perform initial in vivo studies to visualize and ablate pericytes in the mouse brain and heart Selected publications: • Eilken HM, Diéguez-Hurtado R, Schmidt I, Nakayama M, Jeong HW, Arf H, Adams S, Ferrara N, Adams RH (2017): Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1. Nature Communications, 8(1), 1574 • Eilken HM, Adams RH (2010): Dynamics of endothelial cell behavior in sprouting angiogenesis. (Review) Current Opinion in Cell Biology, 22(5), 617-625