Brisbane, Queensland, Australia
School of Enviroment and Science, Griffith Institute for Drug Discovery (GRIDD) and Discovery Biology
Affiliated with Queensland Health (QHealth / QCMHR) and the Queensland Brain Institute (QBI, The University of Queensland). https://sites.google.com/view/giacomotto-lab/home
I am a French scientist strongly attracted by human biology, with a special interest in translational research, genes and diseases, imaging/automatic systems, drug discovery, chemical biology, and medical applications. My work focuses on translating little discoveries made in a single cell or in a model organism to an application or treatment for human. I am working with a wide diversity of models, including cell lines and mouse models, but I recently spent a lot of time working with the zebrafish. I believe that this small animal model will have an important impact in the seek of treatments for neuromuscular and neurological diseases. Those diseases are very difficult to reproduce in a single cell, making the search of drug therapy difficult. This fish opens a new avenue for the screen of bioactive compounds and for understanding the progression of these terrible disorders. I believe in translational research, the zebrafish is for me a fantastic complementary model to cell lines in order to recapitulate human diseases and run large-scale experiments. I work, and will still work with cell lines, zebrafish, mouse and even patients to push all my discoveries in the public world. -Development of animal models of human genetic diseases and research of treatments. -Understanding the function of risk-genes related to motor neuron diseases and schizophrenia.. -Development and maintenance of a translational screening platform (Chemical genetics / Drug discovery). Funding: NHMRC PG (2014-2016, CID) - $441,329 Rebecca L. Cooper (2016, CIA) - $23,900 MNDRIA (2017, CIA) - $99,612 CureSMA (2017-2018, CIA) - US$75,000 CASS Foundation Award (2017, CIA) - $4,000 Nina Buscombe Award (2017, CIA) - $3,000 Canadian CIHR (2018-2023, CIB) - CAD$625,000 Rebecca L. Cooper (2019-2021, CIA) - $100,000 NHMRC PG (2019-2022, CIB) - $481,890 For more information please visit: https://sites.google.com/view/giacomotto-lab/home