United States
Please do everyone a favor by NOT endorsing me - just adds to e-clutter. January 2026: I am in the job market. Probably academic fluorescence microscope core, open to industry position. Currently live in Galveston TX, able to relocate anywhere. For industry position, could relocate wherever needed, travel as needed. Possible to work remotely if appropriate. I just updated my personal web site, https://www.geomcnamara.com , including a new page, https://www.geomcnamara.com/tiki_goddess (whole digital slide image of mouse 40x14 mm mouse tissue section - typical pathology tissue section is 10x10 mm or less). Goal when I was at JHU SOM May 2017 - June 2025: Help cure disease(s) by acquire and analyzing biomedical microscopy images. I now (5/22/2017) manage a fluorescence imaging center at JHU, http://confocal.jhu.edu AND continue to do biomedical consulting on my own time. Experience: Light microscopy, fluorescence microscopy, confocal and multiphoton microscopy, spectral imaging, microscopy image analysis. Spatial Biology --- [FISHscope text moved or deleted - look at other sections]. In 10/2012 I posted online - making it public domain - my Tattletales concept for multiplexing fluorescence reporters in live cells. Please see http://home.earthlink.net/~pubspectra/McNamara_20121023Tue_Tattletales_GFP_Public_Domain.jpg (also discussed further later in my profile here). Co-organizer of PubSpectra with Carl Boswell (U Arizona). For more, see section below and the PubSpectra group. You can find much of my online content at http://works.bepress.com/gmcnamara/ From 2011-~2013 I was a member of the ABRF LMRG - http://www.abrf.org/index.cfm/group.show/LightMicroscopyResearchGroup.54.htm Expert with MDC/UIC MetaMorph, Zeiss Axiovision, ZEN, LSM software, Leica LAS AF software. Microsoft Excel. Manage a Leica AS LMD (mostly use Director slides from www.expressionpathology.com = OncoPlexDX). Some knowledge with: Fiji ImageJ, Becker&Hickl TCSPC FLIM software (part of Leica MP/SP5/FCS/FLIM microscope)(microscope also had ISS FCS/FCCS with 2 APDs on X1 port - essentially unused ... UM should have put the money into 5+ year discounted service contract), digital slide imaging systems from various. Specialties: Light microscopy, fluorescence microscopy, confocal and multiphoton excitation microscopy, fluorescence nanoscopy (aka super-resolution microscopy), spectral imaging, microscopy image analysis; multiplex biosensors Images: I have a few of my favorite images in this section (though linkedin cluelessly chopped off Tiki_Goddess).
May 2025: Elsevier pulled the plug on bepress. PubSpectra data is at https://works.bepress.com/gmcnamara/9 2006 Cytometry abstract (edited for length): The Internet is enabling greater access to spectral imaging publications, spectral graphs, and data than that was available a generation ago. The spectral imaging systems discussed in this issue of Cytometry work because reagent and hardware spectra are reproducible, reusable, and provide input to spectral unmixing and spectral components recognition algorithms. These spectra need to be readily available in order to determine what to purchase, how to use it, and what the output means. We refer to several commercially sponsored and academic spectral web sites and discuss our spectral graphing and data sites. ... Notable among the academic sites, PhotoChemCAD 2.0 has over 200 dyes and a downloadable database/graphing program, and the USC-A Chemistry UV-vis Database displays absorption spectra of many dyes and indicators used in clinical histology and pathology. Our Fluorescent Spectra graphing/calculator site presents dyes, filters, and illumination data from many of these and additional sources. PubSpectra is our free download site which uses Microsoft Excel files as standardized human/machine readable format with over 2,000 biomedical spectra. The principle that data is not subject to copyright provides a framework in which all scientific data should be made freely accessible. McNamara G, Gupta A, Reynaert J, Coates TD, Boswell C 2006 Spectral imaging microscopy web sites and data. Cytometry A 69(8): 863-871. PubMed PMID: 16969821. DOI: 10.1002/cyto.a.20304 http://onlinelibrary.wiley.com/doi/10.1002/cyto.a.20304/abstract See also Garini et al, and other spectral imaging reviews, in same issue. 20210911 update: PubSpectra has not been updated in a long time. I mostly use https://searchlight.semrock.com used extensively to select the components of our FISHscope http://confocal.jhu.edu/current-equipment/fishscope
Biomedical Consultant Innovator - immuno-oncology, light microscopy, image analysis. May 22, 2017: I am now full-time managing a light microscopy core at Johns Hopkins University School of Medicine, http://confocal.jhu.edu. I continue to do biomedical consulting outside JHU. November 16, 2016: I now refer to my multi CAR (or many CAR) concept as "IOcar" with "IO" being both Immuno-Oncology and 10 chimeric antigen receptors, to oncosurfaceome molecules (could be as few as 3, or as many as >>10, with 10 being a good sweet spot). I've posted previously here on linkedin the obvious targets for glioblastoma and many other solid tumors: the overexpresed RTK oncosurfaceome and accessory proteins. Of course 'the devil is in the details' - composition of CAR molecules and cells provide plenty of I.P. opportunities. I see "off the shelf" T-cells (not necessarily text book or J Junk Mouse Immunology subsets) as the future - could start with autologous and/or allogeneic before going completely "off the shelf". Kite Pharma recently mentioned (10/2016 investor's day) that allogeneic hematopoietic stem cell transplant (alloHSCT) "all in" cost is $930,000. Kite and others are now at about 40% complete remission. My thinking is to go for $50K all in for patients who are cured. My current (Sept 2021) edited professional online links Linkedin http://www.linkedin.com/in/georgemcnamara ORCID 0000-0003-4155-0976 Open Researcher and Contributor ID http://orcid.org/ SciENcv https://www.ncbi.nlm.nih.gov/myncbi/george.mcnamara.1/cv/63220/ (NCBI) Note: 10/25/2017 I terminated my ResearchGate account because their terms and conditions were unacceptable. * May 10, 2016 - September 18, 2021 - part time consultant to "confidential CAR T-cell biotech company". My thanks to the staff of the company for the opportunity. I wish them well.
ORCID provides a persistent digital identifier for researchers. The January 3, 2013 issue of Nature has an editorial about identifying researchers with their work. http://www.nature.com/news/in-search-of-credit-1.12117 which I quote in part, "... Of course, it would help to know which John Smith we are talking about. And here is where last year’s launch of the Open Researcher and Contributor ID (ORCID) facility is to be welcomed. The core function of ORCID — a community collaboration (see go.nature.com/sy3qnp) — is to assign every researcher a number and a web page, thereby providing a unique identifier and so disambiguation. The web page enables the researcher to record their contributions: papers they have published and — a facility to come — their research grants and patents. Nature journals authors can link their ORCID to their account in our manuscript submission and tracking system, and we will soon be publishing authors’ ORCIDs in papers. (Readers can register for ORCID here: https://orcid.org/register; see also Nature 485, 564; 2012.)" I encourage all colleagues to register at https://orcid.org/register i just registered (on January 28, 2013) and am adding a little bit of information ... Mu ORCID is 0000-0003-4155-0976. Happy New Year, George
I invented Tattletales and T-Bow on September 12, 2012, during my job interview visit to Cooper lab. My thanks to Brian Rabinovich for introducing me to the 96-TALENs in one click methodology (Reyon et al 2012 Nature Biotechnology, FLASH Assembly). My 2015 update is in http://works.bepress.com/gmcnamara/75 **** My day job is to image and help our lab make more and better serial killers ... cytolytic T-lymphocytes (CD8+ T-cells, CTLs) and natural killer cells (NK cells). I was the microcinematographer for the image at the top, and movie at the bottom of the $100M deal announcement, 1/2015, http://www.cancerfrontline.org/sleeping-beauty-car-t-cells/ ***** To celebrate NIH's October 15, 2012, announcement of funding several Single Cell Analysis Projects, http://www.nih.gov/news/health/oct2012/nibib-15.htm http://commonfund.nih.gov/singlecell/fundedresearch.aspx I am addiing this "position" to my Linkedin Experience list. I have been doing live single cell image acquisition since September 1981, when I joined Bob Furtelle's lab as a graduate student in the Department of Genetics and Development, University of Illinois Urbana-Champaign. ***** Tattletales - I have posted to http://home.earthlink.net/~pubspectra/McNamara_20121023Tue_Tattletales_GFP_Public_Domain.jpg making it Public Domain, my new invention to multiplexfluorescence biosensors and/or gene activity reporters in live cells. I also have a second poster posted online http://home.earthlink.net/~pubspectra/McNamara_20121023Tue_TAM_and_Tattletales_TIK_Public_Domain.jpg part for Temporal Area Maps (TAM) for cell motility analysis, and part on Tattletales. I am looking forward to being able to quantify various Tattletales with cell motility data. The Tattletales poster(s) are on loci in cell nuclei. I expect that knocking down or out Trex and STING (and/or other nucleases and sensors) will enable the DNA platforms to persist in cytoplasm long enough to do experiments.
You can find Tiki_Goddess at http://works.bepress.com/gmcnamara/11/ (Olympus / Hamamatsu NanoZoomer: high resolution) http://works.bepress.com/gmcnamara/1/ (Pathscan) http://home.earthlink.net/~tiki_goddess/ http://home.earthlink.net/~tiki_goddess/TikiGoddess.jpg (original Tiki_Goddess web site and image, respectively). 20210911 update: earthlink 'pulled the plug' on customer web sites (a dumb move in my opinion). Various Tiki_Goddesses can be found at https://works.bepress.com/gmcnamara/ March 2012 update: Tiki_Goddess recieved an honrable mention at the SLAS - JALA & JBS Art of Science Contest Uncovers Beauty of Meaningful Work http://www.eln.slas.org/story/1/57-jala-a-jbs-art-of-science-contest-uncovers-beauty-of-meaningful-work *** October 30, 2017: * I just joined QBI Quantitative Bioimaging Society https://www.quantitativebioimaging.com/society/ * This weekend I installed background art for my profile. From left to right: Temporal Area Maps - one frame from "The Chase" video https://vimeo.com/175151196 Tiki_Goddess head shot behind my head shot (hence this update in this section). PubSpectra https://works.bepress.com/gmcnamara/9/ Tiki_Goddess http://home.earthlink.net/~tiki_goddess/TikiGoddess.jpg