Frank Holland

Senior Principal Research Scientist at Vertex Pharmaceuticals

United States

About

Experience

  • Vertex Pharmaceuticals (7 yrs 11 mos)
    • Senior Principal Research Scientist
      Feb 2024 - Present · 2 yrs 5 mos

    • Principal Research Scientist
      Feb 2022 - Feb 2024 · 2 yrs 1 mo

      -Lead a team of analytical chemists within the Medicinal Chemistry department -Responsible for analytical and purification support across the drug discovery portfolio -High throughput purification by LC-MS and SFC-MS -High Throughput NMR -Physiochemical properties analysis -Laboratory automation

    • Senior Research Scientist
      Feb 2020 - Jan 2022 · 2 yrs

  • Scientist at Alkermes
    Nov 2016 - Aug 2018 · 1 yr 10 mos

    Analytical Development -Developed, validated, and transferred analytical methods for oral solid dosage products -Designed and executed forced degradation studies -Designed and executed accelerated stability studies

  • Research Scientist I at Vertex
    Jan 2011 - Nov 2016 · 5 yrs 11 mos

    Discovery Analytical Chemistry -High Throughput Purification by LC-MS and SFC-MS -Flow NMR -Open Access Instrument Support

  • Senior Research Associate at Momenta Pharmaceuticals
    Jan 2009 - Dec 2010 · 2 yrs

    Analytical Development -Method development and validation in support of API and drug product manufacture -Authored technical documents -Instruments and techniques included HPLC, IC, ELISA, gel electrophoresis

  • Associate Scientist at AstraZeneca
    2007 - 2009 · 2 yrs

    Analytical Support of Medicinal Chemistry -Responsible for chiral purification of medicinal chemistry compounds -Maintained open access analytical equipment -Instrumentation included analytical and preparative HPLC, SFC, and SFC-MS