Frankfurt, Hesse, Germany
- Led biologics scale-up and non-GMP production, ensuring operational readiness, safety, and compliance - Delivered successful tech transfers and capacity-building initiatives across multiple modalities. - Advanced digital transformation (eBR, automated QC sample tables) and represented the site in global pDNA workstreams - Led cross-functional teams on complex, multi-site technical challenges
• Project lead for the implementation of LIMS software in QC GMP labatories • Reported to site management and was involved in budget planing • Succesful execution of the go-live of one out of two milestones • Accelerated timelines for go-live of second milestone • Evaluated feasibility of LIMS implementation in other international sites
• Successfully planned and conducted multiple research projects with the aim of uncovering the link between structural changes of enzymes and their mode of action • Produced and purified various proteins as well as characterized them using several assays and read-outs • Protein engineering based on structural analysis of the conformational landscape and their binding interfaces • Utilized and optimized multiple bioconjugation reactions • Incorporated unnatural amino acids into POI to site-specifically introduce unique functionalities or handles
Upscaling of API synthesis: Planned, conducted and assed novel synthetic pathways
LC-MS and spectroscopic (FI, smFRET) analysis of biomolecules