Basel Metropolitan Area
Specialties: Lead Generation, chemical design, discovery of agrochemicals, hit to lead optimization, molecular modeling, organic reactions and methods, analytical methods for separation and characterization of small molecules, retrosynthetic analysis.
Computer-Assisted Molecular Modeling (CAMM) Group Leader
Development of methodologies for the synthesis of heterocycles, using donor-acceptor (D-A) aminocyclopropanes as reactive intermediates. - Iron-catalysed [3+2] annulation between D-A aminocyclopropanes and aldehydes. - First enantiospecific [3+2] annulation between D-A aminocyclopropanes and ketones. (Prof. J. Waser's group)
Organometallic chemistry- Asymmetric catalysis: - New protocols for the use of dialkyl zinc in asymmetric Reformatsky and aldol-type reactions. Enantioselective organocatalysis: -Development of methodologies for the organocatalytic enantioselective alpha-alkylation of aldehydes via Sn1-type reactions. (Prof. P. G. Cozzi's group)