Philadelphia, Pennsylvania, United States
I am a PhD-trained scientist specializing in CAR T cell engineering and immunotherapy. During my PhD at The Wistar Institute, I investigated how antigen recognition shapes CAR T cell potency and developed multivalent CAR designs to enhance antigen sensitivity and in vivo efficacy. Through my PhD research, I developed strong expertise in overcoming antigen-related limitations, an approach that I am eager to translate to cancer immunotherapy, particularly in the context of solid tumors. I am currently seeking postdoctoral opportunities in CAR T cell therapy and cancer immunotherapy, with a strong interest in translational and mechanistic research.
• Engineered CAR T cells for challenging, low-abundance antigen targets using multivalent designs. • Developed and optimized in vitro and in vivo functional assays to assess CAR T cell properties. • Performed genetic engineering of primary human T cells using lentiviral vectors. • Conducted in vivo studies in humanized mouse models to evaluate CAR T cell therapeutic activity. • Applied flow cytometry-based approaches for phenotypic and functional characterization.